Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.48 |
| ▸ | GABRP | O00591 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11391086 | 0.85 | GABRA1 (0.49) | KDM4EALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL7378323 | 0.85 | GABRA1 (0.54) | KDM4EALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL7384251 | 0.84 | MAPT (0.56) | KDM4EALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL7374173 | 0.81 | GABRA1 (0.56) | KDM4EALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL7380313 | 0.81 | GABRA1 (0.51) | KDM4EALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL7379781 | 0.81 | KDM4E (0.53) | KDM4EALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL7383426 | 0.79 | GABRA1 (0.69) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL7374452 | 0.79 | GABRA1 (0.54) | KDM4EALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL7379711 | 0.77 | GABRA1 (0.54) | KDM4EALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL7385310 | 0.77 | GABRA1 (0.54) | KDM4EALDH1A1LMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010077-A | Tranquilizers | A/S FERROSAN (DK) | 1991-04-23 | — | — | US | disclosed |
| EP-0030254-B1 | BETA-CARBOLIN-3-CARBOXYLIC ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR THERAPEUTICAL USE | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-10-31 | — | — | EP | disclosed |
| US-4371536-A | TRANQUILIZERS | A/S FERROSAN (DK) | 1983-02-01 | — | — | US | disclosed |
| EP-0030254-A1 | Beta-carbolin-3-carboxylic acid derivatives, pharmaceutical compositions containing them and their therapeutical use | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-06-17 | — | — | EP | disclosed |