Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.58 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.58 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.58 |
| ▸ | CPA1 | P15085 | 4/20 | 0.54 |
| ▸ | CPA3 | P15088 | 3/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.54 |
| ▸ | CPB1 | P15086 | 1/20 | 0.54 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.54 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.49 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439697 | 0.84 | CYP1A2 (0.86) | CYP1A2SLC1A3SLC1A2SLC1A1CPA1 | |
| SCHEMBL7432418 | 0.84 | CYP1A2 (0.86) | CYP1A2SLC1A3SLC1A2SLC1A1CPA1 | |
| SCHEMBL9622038 | 0.84 | CYP1A2 (0.86) | CYP1A2SLC1A3SLC1A2SLC1A1CPA1 | |
| SCHEMBL491524 | 0.82 | CYP1A2 (0.83) | CYP1A2SLC1A3SLC1A2SLC1A1CPA1 | |
| SCHEMBL265063 | 0.82 | CYP1A2 (0.83) | CYP1A2SLC1A3SLC1A2SLC1A1CPA1 | |
| SCHEMBL265514 | 0.82 | CYP1A2 (0.83) | CYP1A2SLC1A3SLC1A2SLC1A1CPA1 | |
| SCHEMBL11599447 | 0.81 | CYP1A2 (0.63) | CYP1A2SLC1A3SLC1A2SLC1A1CPA1 | |
| SCHEMBL3928753 | 0.79 | CYP1A2 (0.70) | CYP1A2SLC1A3SLC1A2SLC1A1CPA1 | |
| SCHEMBL4664822 | 0.78 | CYP1A2 (1.00) | CYP1A2SLC1A3SLC1A2SLC1A1CPA1 | |
| SCHEMBL8315228 | 0.77 | CYP1A2 (0.68) | CYP1A2SLC1A3SLC1A2SLC1A1CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154840-A | Antihypertensive pipecolic acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4105776-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS, HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1978-08-08 | — | — | US | disclosed |
| US-4046889-A | HYPOTENSIVE AGENTS, ENZYME INHIBITORS, ANGIOTENSIN CONVERSION | E. R. SQUIBB & SONS, INC. (US) | 1977-09-06 | — | — | US | disclosed |