SCHEMBL738263

SCHEMBL738263

CC(N)CCC[C@H](N)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 2/20 0.58
ARG2 P78540 4/20 0.52
ARG1 P05089 3/20 0.52
NOS2 P35228 6/20 0.52
NOS1 P29475 5/20 0.52
NOS3 P29474 4/20 0.52
CYP2C19 P33261 2/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
CYP1A2 P05177 3/20 0.50
GABRP O00591 2/20 0.50
GABRD O14764 2/20 0.50
GABRA1 P14867 2/20 0.50
GABRB1 P18505 2/20 0.50
GABRG2 P18507 2/20 0.50
GABRB3 P28472 2/20 0.50
GABRA5 P31644 2/20 0.50
GABRA3 P34903 2/20 0.50
GABRA2 P47869 2/20 0.50
GABRB2 P47870 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17281360 1.00 GSR (0.58) GSRARG2ARG1NOS2NOS1
SCHEMBL4435999 1.00 GSR (0.58) GSRARG2ARG1NOS2NOS1
SCHEMBL433668 1.00 GSR (0.58) GSRARG2ARG1NOS2NOS1
SCHEMBL16577962 0.95 GSR (0.64) GSRARG2ARG1NOS2NOS1
SCHEMBL13369016 0.95 GSR (0.64) GSRARG2ARG1NOS2NOS1
SCHEMBL15987065 0.87 GSR (0.71) GSRARG2ARG1NOS2NOS1
SCHEMBL13703207 0.87 GSR (0.50) GSRARG2ARG1NOS2NOS1
SCHEMBL29289 0.87 GSR (0.71) GSRARG2ARG1NOS2NOS1
SCHEMBL10135848 0.87 GSR (0.71) GSRARG2ARG1NOS2NOS1
SCHEMBL29291 0.87 GSR (0.71) GSRARG2ARG1NOS2NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2010524472-A 2010-07-22 JP claimed
EP-2147116-A1 STABLE RECOMBINANT ADENOSINE DEAMINASE Enzon Pharmaceuticals, Inc. (US) 2010-01-27 EP claimed
US-20090047271-A1 STABLE RECOMBINANT ADENOSINE DEAMINASE ENZON PHARMACEUTICALS, INC. (US) 2009-02-19 US claimed
WO-2008131208-A1 STABLE RECOMBINANT ADENOSINE DEAMINASE ENZON PHARMACEUTICALS, INC. (US) 2008-10-30 WO claimed
CN-1237171-C Enzymatic deprotection of amines and hydroxides BRISTOL MYERS SQUIBB CO (US) 2006-01-18 CN claimed
US-6828119-B2 Deprotecting a hydroxide or amine; obtain sample, incubate with enzyme, remoe protecting group, recover amine BRISTOL MYERS SQUIBB COMPANY 2004-12-07 US claimed
CN-1484695-A Enzymatic deprotection of amines and hydroxides ����˹�ж�-����˹˹������˾ 2004-03-24 CN claimed
EP-1348025-A2 ENZYMATIC DEPROTECTION OF AMINES AND HYDROXIDES Bristol-Myers Squibb Company (US) 2003-10-01 EP claimed
US-20020123110-A1 Enzymatic deprotection of amines and hydroxides BRISTOL-MYERS SQUIBB COMPANY 2002-09-05 US claimed
WO-2002053724-A2 ENZYMATIC DEPROTECTION OF AMINES AND HYDROXIDES BRISTOL-MYERS SQUIBB COMPANY (US) 2002-07-11 WO claimed
WO-2025122670-A1 FORMULATIONS FOR DUAL VEGF/IL-6 INHIBITORS, ANTI-VEGF ANTIBODIES, AND CONJUGATES THEREOF KODIAK SCIENCES INC. (US) 2025-06-12 WO disclosed
US-20250154198-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR ZEALAND PHARMA A/S (DK) 2025-05-15 US disclosed
EP-4440592-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR Zealand Pharma A/S (DK) 2024-10-09 EP disclosed
CN-118354781-A Peptide inhibitors of interleukin-23 receptor 西兰制药公司 2024-07-16 CN disclosed
WO-2023217679-A1 MASS-TAG LABELING OF THE CELLULAR SECRETOME THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2023-11-16 WO disclosed
US-4665052-A HOMOPHENYLALANINE, HYPOTENSIVES, ANTIALDOSTERONES MERCK & CO., INC. (US) 1987-05-12 US disclosed
EP-0158057-A1 Salts of oxazaphosphorine derivatives ASTA Pharma AG (DE) 1985-10-16 EP disclosed
EP-0156320-A2 Renin inhibitors containing homophe 8 and a C-terminal amide cycle MERCK & CO. INC. (US) 1985-10-02 EP disclosed
EP-0129189-A2 Renin inhibitors containing a C-terminal amide cycle and compositions and combinations containing the same MERCK & CO. INC. (US) 1984-12-27 EP disclosed
US-4485099-A HYPOTENSIVE AGENTS/,ANTIALDOSTERONES MERCK & CO., INC. (US) 1984-11-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090047271-A1 STABLE RECOMBINANT ADENOSINE DEAMINASE ADA, CDA, DCTD GSR 329/4885ARG2 1011/4885ARG1 1904/4885
US-20250154198-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR IL23R, IL1RN, IL33 GSR 2148/4885ARG2 2942/4885ARG1 1043/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.