SCHEMBL738264

SCHEMBL738264

CC(C)(C)[Si](C)(C)OCCO

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DUT P33316 2/20 0.34
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10126610 0.86 MEN1 (0.48) DUTALDH1A1TSHRMAPK1MEN1
SCHEMBL4968784 0.86 MEN1 (0.48) DUTALDH1A1TSHRMAPK1MEN1
SCHEMBL2832489 0.86 MEN1 (0.48) DUTALDH1A1TSHRMAPK1MEN1
SCHEMBL2829406 0.86 MEN1 (0.48) DUTALDH1A1TSHRMAPK1MEN1
SCHEMBL1936442 0.86 MEN1 (0.48) DUTALDH1A1TSHRMAPK1MEN1
SCHEMBL15345824 0.86 MEN1 (0.48) DUTALDH1A1TSHRMAPK1MEN1
SCHEMBL15750871 0.85 DUT (0.32) DUT
SCHEMBL571057 0.85 DUT (0.39) DUT
Ammonia Solution, Strong SCHEMBL9187414 0.83 DUT (0.38) DUT
SCHEMBL334934 0.83 DUT (0.38) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 921 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117534646-B Preparation method of procyanidine B2 朗华生物科学(深圳)有限公司 2025-02-25 CN claimed
CN-118239787-A Ground silicon nitride ceramic chip 江苏富乐华功率半导体研究院有限公司 2024-06-25 CN claimed
CN-115093657-B Wear-resistant PVC material and application thereof 广东亮丰达实业有限公司 2024-04-30 CN claimed
CN-117658967-A Preparation method of flavan-3, 4-diol derivative 朗华生物科学(深圳)有限公司 2024-03-08 CN claimed
CN-117534646-A Preparation method of procyanidine B2 朗华生物科学(深圳)有限公司 2024-02-09 CN claimed
CN-116813641-A Preparation method of everolimus 杭州华东医药集团康润制药有限公司 2023-09-29 CN claimed
CN-114853831-B Antitumor compound and preparation method and application thereof 四川瑞泽健科技有限公司 2023-09-19 CN claimed
CN-113801303-B Method and device for preparing polylactic acid 北京工商大学 2023-07-18 CN claimed
CN-115093657-A Wear-resistant PVC material and application thereof 广东亮丰达实业有限公司 2022-09-23 CN claimed
CN-114853831-A Antitumor compound and preparation method and application thereof 四川瑞泽健科技有限公司 2022-08-05 CN claimed
EP-3539968-B1 NOVEL TRITYL PROTECTING AGENT SEKISUI MEDICAL CO LTD (JP) 2021-07-14 EP claimed
US-10981940-B2 Trityl protecting agent SEKISUl MEDICAL CO., LTD. (JP) 2021-04-20 US claimed
CN-108795289-B Nano titanium surface loaded Si, Cu-TiO 2Preparation method of antibacterial bioactive film layer 温州医科大学附属口腔医院 2020-07-17 CN claimed
CN-106153755-B Analysis and detection method of 2- (tert-butyl dimethyl silicon alkyloxy) ethanol 山东新时代药业有限公司 2020-02-14 CN claimed
US-20190308997-A1 NOVEL TRITYL PROTECTING AGENT SEKISUI MEDICAL CO., LTD. (JP) 2019-10-10 US claimed
EP-3539968-A1 NOVEL TRITYL PROTECTING AGENT Sekisui Medical Co., Ltd. (JP) 2019-09-18 EP claimed
US-9938297-B2 Process for the synthesis of everolimus and intermediates thereof Cipia Limited (IN) 2018-04-10 US claimed
US-20170217988-A1 Process for the Synthesis of Everolimus and Intermediates Thereof CIPLA LIMITED (IN) 2017-08-03 US claimed
EP-3166950-A1 PROCESS FOR THE SYNTHESIS OF EVEROLIMUS AND INTERMEDIATES THEREOF Cipla Limited (IN) 2017-05-17 EP claimed
WO-2016020664-A1 PROCESS FOR THE SYNTHESIS OF EVEROLIMUS AND INTERMEDIATES THEREOF CIPLA LIMITED (IN) 2016-02-11 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10981940-B2 Trityl protecting agent POT1, TXNL1, TXLNA DUT 4663/4885ALDH1A1 1839/4885TSHR 482/4885
US-20170217988-A1 Process for the Synthesis of Everolimus and Intermediates Thereof MTOR, RICTOR, RPTOR DUT 1092/4885ALDH1A1 2765/4885TSHR 4306/4885
US-20190308997-A1 NOVEL TRITYL PROTECTING AGENT POT1, TXNL1, TXLNA DUT 4627/4885ALDH1A1 1482/4885TSHR 571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.