Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4892289 | 0.91 | — | — | |
| SCHEMBL1721038 | 0.74 | — | — | |
| SCHEMBL12494175 | 0.73 | MAPT (0.36) | — | |
| SCHEMBL12494103 | 0.73 | — | — | |
| SCHEMBL15321448 | 0.70 | — | — | |
| SCHEMBL7831061 | 0.68 | — | — | |
| SCHEMBL611093 | 0.67 | — | — | |
| SCHEMBL5569849 | 0.66 | — | — | |
| SCHEMBL2598070 | 0.66 | — | — | |
| SCHEMBL1866638 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254561-A | Tricyclic antipsychotic agents | MERCK SHARP & DOHME LIMITED (GB) | 1993-10-19 | — | — | US | disclosed |
| EP-0463691-A2 | Tricyclic sigma ligands | MERCK SHARP & DOHME LTD. (GB) | 1992-01-02 | — | — | EP | disclosed |