Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27277369 | 0.85 | PPARG (0.59) | PPARG | |
| SCHEMBL7381222 | 0.85 | PPARG (0.60) | PPARG | |
| SCHEMBL9751930 | 0.84 | PPARG (0.79) | PPARG | |
| SCHEMBL2721340 | 0.83 | PPARG (0.58) | PPARG | |
| SCHEMBL7415561 | 0.83 | PPARG (0.58) | PPARG | |
| SCHEMBL7985187 | 0.82 | PPARG (0.57) | PPARG | |
| SCHEMBL29131650 | 0.80 | PPARG (0.55) | PPARG | |
| SCHEMBL3893774 | 0.79 | L3MBTL1 (0.60) | PPARG | |
| SCHEMBL3893777 | 0.79 | L3MBTL1 (0.60) | PPARG | |
| SCHEMBL28440258 | 0.79 | PPARG (0.54) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291511-B1 | Biarylalkanoic acids as cell adhesion inhibitors | MERCK & CO., INC. | 2001-09-18 | — | — | US | disclosed |
| EP-1017382-A4 | BIARYLALKANOIC ACIDS AS CELL ADHESION INHIBITORS | MERCK & CO INC (US) | 2000-08-30 | — | — | EP | disclosed |
| EP-1017382-A1 | BIARYLALKANOIC ACIDS AS CELL ADHESION INHIBITORS | Merck & Co., Inc. (a New Jersey corp.) (US) | 2000-07-12 | — | — | EP | disclosed |
| WO-1998053817-A1 | BIARYLALKANOIC ACIDS AS CELL ADHESION INHIBITORS | MERCK & CO., INC. (US) | 1998-12-03 | — | — | WO | disclosed |