⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11228696 | 1.00 | — | — | |
| SCHEMBL738391 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL2028219 | 0.98 | — | — | |
| SCHEMBL7005905 | 0.77 | — | — | |
| SCHEMBL22051472 | 0.77 | — | — | |
| SCHEMBL11728551 | 0.77 | — | — | |
| SCHEMBL22201957 | 0.73 | BRD4 (0.41) | — | |
| SCHEMBL8001289 | 0.73 | BRD4 (0.41) | — | |
| SCHEMBL24764025 | 0.71 | INMT (0.39) | — | |
| SCHEMBL22051471 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4226595-A | Oxidation hair-coloring preparation based upon N,N-bis-(β-hydroxyethyl)-m-phenylenediamines | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1980-10-07 | — | — | US | claimed |
| EP-1498411-B9 | DIKETOHYDRAZINE DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2013-12-04 | — | — | EP | disclosed |
| EP-1498411-B1 | DIKETOHYDRAZINE DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-8138182-B2 | Diketohydrazine derivative compounds and drugs containing the compounds as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2012-03-20 | — | — | US | disclosed |
| US-20100087442-A1 | DIKETOHYDRAZINE DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD (JP) | 2010-04-08 | — | — | US | disclosed |
| US-7655804-B2 | N-[(1S)-3-{(2Z)-2-[(4R)-3,4-dimethyl-1,3-thiazolidin-2-ylidene]hydrazino}-2,3-dioxo-1-(tetrahydro-2H-pyran-4-yl)propyl]cycloheptanecarboxamide; cysteine protease inhibitors; for the treatment of inflammatory, immune, ischemic, respiratory,circulatory, neuronal, blood, hepatic and metabolic diseases | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-02-02 | — | — | US | disclosed |
| US-20060111303-A1 | Diketohydrazine derivative compounds and drugs contaiing the compounds as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-05-25 | — | — | US | disclosed |
| EP-1498411-A1 | DIKETOHYDRAZINE DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-01-19 | — | — | EP | disclosed |
| WO-1996005799-A1 | HAIR DYE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1996-02-29 | — | — | WO | disclosed |
| EP-0524215-A1 | OXIDATION PIGMENTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 1993-01-27 | — | — | EP | disclosed |
| EP-0039807-A2 | Hair-dyeing compositions | Henkel Kommanditgesellschaft auf Aktien (DE) | 1981-11-18 | — | — | EP | disclosed |
| EP-0039034-A1 | Coupling components for the oxidative dyeing of hair and their use, as well as compositions containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1981-11-04 | — | — | EP | disclosed |
| EP-0039030-A1 | Coupler components for oxidative hair dyes, their preparation and their use, and hair dyeing compositions containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1981-11-04 | — | — | EP | disclosed |
| EP-0036591-A1 | Coupler components for oxidation hair dyes, their preparation and use, and hair dyes containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1981-09-30 | — | — | EP | disclosed |
| EP-0030680-A1 | Hair dye compositions | Henkel Kommanditgesellschaft auf Aktien (DE) | 1981-06-24 | — | — | EP | disclosed |
| EP-0029964-A1 | Coupler components for oxidation hair dyes, their production and use, and hair dyeing compositions containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1981-06-10 | — | — | EP | disclosed |
| EP-0023257-A1 | Dichloro-hydroxyethylamino phenols, process for their production, their use and hair dyeing compositions containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1981-02-04 | — | — | EP | disclosed |
| US-4226595-A | Oxidation hair-coloring preparation based upon N,N-bis-(β-hydroxyethyl)-m-phenylenediamines | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1980-10-07 | — | — | US | disclosed |
| EP-0011844-A1 | Coupling components for oxidizing hair dyes, their preparation and hair dyes containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1980-06-11 | — | — | EP | disclosed |
| EP-0002828-A2 | Hair dyeing composition | Henkel Kommanditgesellschaft auf Aktien (DE) | 1979-07-11 | — | — | EP | disclosed |