Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7381326 | 1.00 | MEN1 (0.44) | MEN1KMT2AALDH1A1GAAKDM4E | |
| SCHEMBL7379863 | 1.00 | MEN1 (0.44) | MEN1KMT2AALDH1A1GAAKDM4E | |
| SCHEMBL7385425 | 0.90 | KCNQ2 (0.39) | MEN1KMT2AALDH1A1KDM4ECHRM2 | |
| SCHEMBL7383686 | 0.88 | BLM (0.39) | MEN1KMT2AKDM4ECHRM2CHRM5 | |
| SCHEMBL7378937 | 0.88 | KCNQ2 (0.40) | MEN1KMT2AGAAKDM4ECHRM2 | |
| SCHEMBL7383592 | 0.88 | CHRM2 (0.39) | MEN1KMT2AALDH1A1KDM4ECHRM2 | |
| SCHEMBL7381276 | 0.86 | GAA (0.42) | KMT2AGAACYP19A1CYP17A1L3MBTL1 | |
| SCHEMBL7388484 | 0.85 | HTT (0.41) | MEN1KMT2AALDH1A1KDM4ECYP19A1 | |
| SCHEMBL7387023 | 0.85 | KCNQ2 (0.45) | KDM4EPOLBL3MBTL1 | |
| SCHEMBL7387268 | 0.84 | GPBAR1 (0.39) | MEN1KMT2AALDH1A1CHRM2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281617-A | Enzyme inhibitor | CORTECH, INC. (US) | 1994-01-25 | — | — | US | claimed |
| EP-1216230-A2 | FUSED CYCLOHEPTANE AND FUSED AZACYCLOHEPTANE COMPOUNDS AND THEIR USE AS INTEGRIN RECEPTOR ANTAGONISTS | Amgen Inc. (US) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001023357-A2 | FUSED CYCLOHEPTANE AND FUSED AZACYCLOHEPTANE COMPOUNDS AND THEIR USE AS INTEGRIN RECEPTOR ANTAGONISTS | AMGEN INC. (US) | 2001-04-05 | — | — | WO | disclosed |
| US-5281617-A | Enzyme inhibitor | CORTECH, INC. (US) | 1994-01-25 | — | — | US | disclosed |