SCHEMBL7384306

SCHEMBL7384306

CC(C)Oc1ccc(NC2CCN(C(=O)OC(C)(C)C)CC2)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.76
MAPT P10636 2/20 0.74
NPC1 O15118 2/20 0.74
RAB9A P51151 2/20 0.74
MAPK1 P28482 1/20 0.74
HTT P42858 1/20 0.74
L3MBTL1 Q9Y468 1/20 0.74
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA9 Q16790 1/20 0.53
PTPN2 P17706 1/20 0.52
PTPN1 P18031 1/20 0.52
PTPN6 P29350 1/20 0.52
GPR119 Q8TDV5 4/20 0.48
EPHX1 P07099 1/20 0.47
STS P08842 1/20 0.46
ABL1 P00519 1/20 0.46
RIN1 Q13671 1/20 0.46
CNR1 P21554 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4109009 0.86 ALDH1A1 (1.00) ALDH1A1MAPTNPC1RAB9AMAPK1
SCHEMBL7385548 0.85 ALDH1A1 (1.00) ALDH1A1MAPTNPC1RAB9AMAPK1
SCHEMBL23742317 0.85 ALDH1A1 (0.71) ALDH1A1MAPTNPC1RAB9AMAPK1
SCHEMBL4247075 0.84 ALDH1A1 (0.78) ALDH1A1MAPTNPC1RAB9AMAPK1
SCHEMBL17554400 0.84 ALDH1A1 (0.77) ALDH1A1MAPTNPC1RAB9AMAPK1
SCHEMBL4115820 0.84 ALDH1A1 (0.77) ALDH1A1MAPTNPC1RAB9AMAPK1
SCHEMBL10210061 0.84 ALDH1A1 (0.79) ALDH1A1MAPTNPC1RAB9AMAPK1
SCHEMBL23742318 0.83 ALDH1A1 (0.76) ALDH1A1MAPTNPC1RAB9AMAPK1
SCHEMBL4120409 0.83 ALDH1A1 (0.76) ALDH1A1MAPTNPC1RAB9AMAPK1
SCHEMBL382304 0.83 ALDH1A1 (0.76) ALDH1A1MAPTNPC1RAB9AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6251919-B1 ADMINISTERING ANILINE DERIVATIVE FOR THERAPY OF PAIN WARNER-LAMBERT 2001-06-26 US disclosed
WO-1999043658-A1 HETEROCYCLIC SUBSTITUTED ANILINE CALCIUM CHANNEL BLOCKERS WARNER-LAMBERT COMPANY (US) 1999-09-02 WO disclosed