Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.30 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4715109 | 0.94 | SSTR4 (0.52) | SSTR4CA14NR3C1HTR2CSLC6A4 | |
| SCHEMBL4718059 | 0.81 | SSTR4 (0.50) | SSTR4CA14RIPK1HDAC1HSD17B10 | |
| SCHEMBL4719084 | 0.80 | SSTR4 (0.46) | SSTR4CA14HDAC1KDM4EALDH1A1 | |
| SCHEMBL4718013 | 0.77 | SSTR4 (0.43) | SSTR4CA14ALDH1A1HPGD | |
| SCHEMBL25047728 | 0.77 | SSTR4 (0.48) | SSTR4CA14RIPK1GRM2HDAC1 | |
| SCHEMBL4715979 | 0.77 | SSTR4 (0.43) | SSTR4NR3C1HTR2CSLC6A4HTR2A | |
| SCHEMBL4715976 | 0.77 | SSTR4 (0.43) | SSTR4NR3C1HTR2CSLC6A4HTR2A | |
| SCHEMBL12715855 | 0.76 | GRM2 (0.43) | SSTR4NR3C1HTR2CSLC6A4HTR2A | |
| SCHEMBL23105683 | 0.75 | RIPK1 (0.49) | SSTR4NR3C1HTR2CSLC6A4HTR2A | |
| SCHEMBL14762235 | 0.75 | SSTR4 (0.52) | SSTR4CA14HTR2CSLC6A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216230-A2 | FUSED CYCLOHEPTANE AND FUSED AZACYCLOHEPTANE COMPOUNDS AND THEIR USE AS INTEGRIN RECEPTOR ANTAGONISTS | Amgen Inc. (US) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001023357-A2 | FUSED CYCLOHEPTANE AND FUSED AZACYCLOHEPTANE COMPOUNDS AND THEIR USE AS INTEGRIN RECEPTOR ANTAGONISTS | AMGEN INC. (US) | 2001-04-05 | — | — | WO | disclosed |