Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.70 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.70 |
| ▸ | F7 | P08709 | 6/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | ITGAV | P06756 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7385648 | 1.00 | ITGB3 (0.70) | ITGB3ITGA2BF7F2CYP2C9 | |
| SCHEMBL7391723 | 0.91 | ITGB3 (0.79) | ITGB3ITGA2BF7F2ITGAV | |
| SCHEMBL7387179 | 0.88 | ITGB3 (0.55) | ITGB3ITGA2BF7F2CYP2C9 | |
| SCHEMBL7387186 | 0.88 | ITGB3 (0.55) | ITGB3ITGA2BF7F2CYP2C9 | |
| SCHEMBL7385119 | 0.86 | ITGB3 (0.72) | ITGB3ITGA2BF7F2CYP2C9 | |
| SCHEMBL7387587 | 0.86 | ITGB3 (0.72) | ITGB3ITGA2BF7F2CYP2C9 | |
| SCHEMBL9390830 | 0.86 | ITGB3 (0.72) | ITGB3ITGA2BF7F2CYP2C9 | |
| SCHEMBL9389691 | 0.84 | ITGB3 (0.77) | ITGB3ITGA2BF7F2 | |
| SCHEMBL7385792 | 0.84 | ITGB3 (0.77) | ITGB3ITGA2BF7F2 | |
| SCHEMBL7390910 | 0.83 | ITGB3 (0.68) | ITGB3ITGA2BF7F2ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994017041-A1 | AMIDINOPHENYL SUBSTITUTED UREA, THIOUREA OR GUANIDINO DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-08-04 | — | — | WO | claimed |
| US-5624956-A | Urea derivatives useful as platelet aggregation inhibitors | THE MONSANTO COMPANY (US) | 1997-04-29 | — | — | US | disclosed |
| US-5475025-A | Urea derivatives useful as platelet aggregation inhibitors | THE MONSANTO COMPANY (US) | 1995-12-12 | — | — | US | disclosed |
| WO-1994017041-A1 | AMIDINOPHENYL SUBSTITUTED UREA, THIOUREA OR GUANIDINO DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-08-04 | — | — | WO | disclosed |
| US-5314902-A | Thioureas and guanidine compounds, anticoagulants | MONSANTO COMPANY (US) | 1994-05-24 | — | — | US | disclosed |