Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.76 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.76 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389300 | 0.86 | ITGB3 (1.00) | ITGB3ITGA2BST14LMNATSHR | |
| SCHEMBL7383404 | 0.85 | ITGB3 (0.60) | ITGB3ITGA2BST14S1PR1LMNA | |
| SCHEMBL7384469 | 0.84 | ITGB3 (0.59) | ITGB3ITGA2BST14S1PR1LMNA | |
| SCHEMBL7387496 | 0.83 | ITGB3 (0.54) | ITGB3ITGA2BST14 | |
| SCHEMBL7379988 | 0.83 | ITGB3 (0.88) | ITGB3ITGA2BST14LMNATSHR | |
| SCHEMBL289158 | 0.82 | ITGB3 (0.74) | ITGB3ITGA2BST14 | |
| SCHEMBL12348109 | 0.82 | EPHX2 (0.63) | ITGB3ITGA2BST14EPHX2 | |
| SCHEMBL7421017 | 0.81 | ITGB3 (0.61) | ITGB3ITGA2BST14S1PR1 | |
| SCHEMBL7422860 | 0.81 | ITGB3 (0.61) | ITGB3ITGA2BST14S1PR1 | |
| SCHEMBL7412408 | 0.81 | ITGB3 (0.61) | ITGB3ITGA2BST14LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344837-A | Platelet aggregation inhibitors | G.D. SEARLE & CO. (US) | 1994-09-06 | — | — | US | disclosed |
| WO-1994001396-A1 | PHENYL AMIDINE UREA DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-01-20 | — | — | WO | disclosed |
| US-5272162-A | Platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1993-12-21 | — | — | US | disclosed |