⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL11046587 | 0.78 | ENTPD5 (0.32) | — | |
| Ammonia Solution, Strong SCHEMBL6551899 | 0.78 | — | — | |
| SCHEMBL24685640 | 0.76 | — | — | |
| Ammonia Solution, Strong SCHEMBL7167292 | 0.76 | GAA (0.34) | — | |
| SCHEMBL175993 | 0.73 | — | — | |
| SCHEMBL9766073 | 0.73 | — | — | |
| Ammonia Solution, Strong SCHEMBL8107688 | 0.72 | — | — | |
| SCHEMBL16448401 | 0.72 | — | — | |
| SCHEMBL10260567 | 0.72 | SHBG (0.36) | — | |
| SCHEMBL6847867 | 0.72 | SHBG (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106179492-B | The revivifier and rejuvenation method and purposes of MTP decaying catalyst | 山东齐鲁科力化工研究院有限公司 | 2019-01-15 | — | — | CN | disclosed |
| CN-106179530-B | Extend the method and purposes of catalyst for producing propylene with methanol operation cycle | 山东齐鲁科力化工研究院有限公司 | 2019-01-11 | — | — | CN | disclosed |
| CN-106179491-B | The revivifier aqueous solution and its rejuvenation method of MTP decaying catalyst | 山东齐鲁科力化工研究院有限公司 | 2019-01-11 | — | — | CN | disclosed |
| CN-106179492-A | The revivifier of MTP decaying catalyst and rejuvenation method and purposes | 山东齐鲁科力化工研究院有限公司 | 2016-12-07 | — | — | CN | disclosed |
| CN-104447702-B | A kind of amido replaces Bouchardatine derivant and its preparation method and application | 中山大学 | 2016-12-07 | — | — | CN | disclosed |
| CN-106179491-A | The revivifier aqueous solution of MTP decaying catalyst and rejuvenation method thereof | 山东齐鲁科力化工研究院有限公司 | 2016-12-07 | — | — | CN | disclosed |
| CN-106179530-A | Extend method and the purposes of catalyst for producing propylene with methanol service cycle | 山东齐鲁科力化工研究院有限公司 | 2016-12-07 | — | — | CN | disclosed |
| CN-104447702-A | Amidogen substituted Bouchardatine derivative as well as preparation method and application thereof | UNIV SUN YAT SEN | 2015-03-25 | — | — | CN | disclosed |
| CN-102131782-B | Pyridine derivatives as VEGF-2 receptor and protein tyrosine kinase inhibitors | LEO PHARMA AS | 2014-07-30 | — | — | CN | disclosed |
| CN-102600162-A | Pyridazine derivatives and their use as therapeutic agents | XENON PHARMACEUTICALS INC | 2012-07-25 | — | — | CN | disclosed |
| CN-102131782-A | Pyridine derivatives as VEGF-2 receptor and protein tyrosine kinase inhibitors | LEO PHARMA AS | 2011-07-20 | — | — | CN | disclosed |
| CN-101160289-A | Pyridazine derivatives and their use as therapeutic agents | XENON PHARMACEUTICALS INC (CA) | 2008-04-09 | — | — | CN | disclosed |
| CN-101083982-A | Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-coa desaturase enzymes | XENON PHARMACEUTICALS INC (CA) | 2007-12-05 | — | — | CN | disclosed |
| CN-1789242-A | Method for preparing 2-substituted carbamide by reaction of amine and carbon dioxide | LANZHOU CHEM PHYS INST (CN) | 2006-06-21 | — | — | CN | disclosed |
| CN-1681498-A | Diaryl ethers as opioid receptor antagonist | LILLY CO ELI (US) | 2005-10-12 | — | — | CN | disclosed |
| EP-1003751-A1 | HYDROXAMIC ACID SUBSTITUTED FUSED HETEROCYCLIC METALLOPROTEINASE INHIBITORS | AMGEN INC. (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999006410-A1 | HYDROXAMIC ACID SUBSTITUTED FUSED HETEROCYCLIC METALLOPROTEINASE INHIBITORS | AMGEN INC. (US) | 1999-02-11 | — | — | WO | disclosed |