Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 5/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | CCR3 | P51677 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 2/20 | 0.48 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.47 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.47 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7387362 | 0.91 | MAOB (0.47) | KCNH2ACHESIGMAR1MAOBCCR3 | |
| SCHEMBL7391864 | 0.81 | SIGMAR1 (0.58) | ACHESIGMAR1MAOBHTR6 | |
| SCHEMBL7392437 | 0.80 | MAOB (0.56) | ACHESIGMAR1MAOBHTR6 | |
| SCHEMBL30380307 | 0.79 | SIGMAR1 (0.60) | SIGMAR1MAOBHTR6CARM1PRMT6 | |
| SCHEMBL5368437 | 0.78 | SIGMAR1 (0.75) | SIGMAR1CCR3 | |
| SCHEMBL19040059 | 0.77 | SIGMAR1 (0.55) | ACHESIGMAR1MAOB | |
| SCHEMBL5365334 | 0.77 | SIGMAR1 (0.68) | SIGMAR1CCR3 | |
| SCHEMBL2353465 | 0.76 | SIGMAR1 (0.59) | ACHESIGMAR1MAOBHTR6 | |
| Hydrochloric Acid SCHEMBL7255708 | 0.74 | SIGMAR1 (0.58) | ACHESIGMAR1MAOBHTR6 | |
| SCHEMBL29733117 | 0.74 | SIGMAR1 (0.85) | ACHESIGMAR1MAOBCARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0873990-A1 | BENZOIC ACID COMPOUNDS AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-10-28 | — | — | EP | disclosed |