Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.55 |
| ▸ | REN | P00797 | 4/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PEPD | P12955 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21348091 | 0.90 | ACE2 (0.48) | ACERENACE2KDM4EF2 | |
| SCHEMBL10552189 | 0.86 | ACE (0.65) | ACERENACE2KDM4EF2 | |
| SCHEMBL10552185 | 0.86 | ACE (0.65) | ACERENACE2KDM4EF2 | |
| SCHEMBL30051880 | 0.86 | REN (0.53) | ACERENACE2KDM4EF2 | |
| SCHEMBL30051550 | 0.86 | ACE (0.51) | ACERENACE2KDM4EF2 | |
| SCHEMBL15692328 | 0.85 | ACE (0.52) | ACERENACE2KDM4EF2 | |
| SCHEMBL29794187 | 0.85 | ACE (0.50) | ACERENACE2KDM4EF2 | |
| SCHEMBL28346593 | 0.84 | XIAP (0.50) | ACE2KMT2A | |
| SCHEMBL30051606 | 0.84 | ACE (0.49) | ACERENACE2KDM4EF2 | |
| SCHEMBL30661443 | 0.84 | ACE (0.49) | ACERENACE2KDM4EF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110627867-A | Peptide-like small molecule compound acting on MLL fusion protein | 中国药科大学 | 2019-12-31 | — | — | CN | disclosed |
| EP-0639585-A1 | Elastase inhibitor | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-02-22 | — | — | EP | disclosed |