Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6661843 | 1.00 | KMT2A (0.56) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| Hydrochloric Acid SCHEMBL6661836 | 0.99 | KMT2A (0.55) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| Hydrochloric Acid SCHEMBL6661838 | 0.99 | KMT2A (0.55) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL2890222 | 0.88 | KMT2A (0.58) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL7613530 | 0.87 | PPARG (0.49) | KMT2ATDP1LMNAMAPTALDH1A1 | |
| SCHEMBL27505413 | 0.86 | KMT2A (0.59) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL616963 | 0.86 | ALPI (0.61) | KMT2AALDH1A1MEN1PPARGPKM | |
| SCHEMBL132409 | 0.86 | ALPI (0.61) | KMT2AALDH1A1MEN1PPARGPKM | |
| SCHEMBL132790 | 0.86 | ALPI (0.61) | KMT2AALDH1A1MEN1PPARGPKM | |
| Hydrochloric Acid SCHEMBL216055 | 0.84 | ALPI (0.59) | KMT2AALDH1A1MEN1PPARGPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197794-B1 | ANTIINFLAMAMTORY AGENTS; IMMUNOLOGY DISEASES | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-03-06 | — | — | US | disclosed |
| EP-1044215-A1 | ANTI-INFLAMMATORY PHENYLALANINE DERIVATIVES | CELLTECH THERAPEUTICS LIMITED (GB) | 2000-10-18 | — | — | EP | disclosed |
| WO-1999035163-A1 | PHENYLALANINE DERIVATIVES | CELLTECH THERAPEUTICS LIMITED (GB) | 1999-07-15 | — | — | WO | disclosed |