Sugi Predict

Sugi Predict / Compounds / SCHEMBL132409

SCHEMBL132409

SCHEMBL132409

CCOC(=O)[C@H](N)Cc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALPI P09923 1/20 0.61
▸ PKM P14618 1/20 0.61
▸ PTGS1 P23219 1/20 0.61
▸ XIAP P98170 1/20 0.61
▸ SLC7A5 Q01650 1/20 0.61
▸ MMP8 P22894 1/20 0.58
▸ SLC15A1 P46059 2/20 0.53
▸ LTA4H P09960 1/20 0.50
▸ SLC1A3 P43003 2/20 0.49
▸ SLC1A2 P43004 2/20 0.49
▸ SLC1A1 P43005 2/20 0.49
▸ PIN1 Q13526 1/20 0.49
▸ ALDH1A1 P00352 2/20 0.48
▸ EPHX2 P34913 1/20 0.48
▸ PPARG P37231 1/20 0.48
▸ TP53 P04637 1/20 0.48
▸ HDAC8 Q9BY41 1/20 0.47
▸ MEN1 O00255 1/20 0.47
▸ NPC1 O15118 1/20 0.47
▸ KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132790 1.00 ALPI (0.61) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL616963 1.00 ALPI (0.61) ALPIPKMPTGS1XIAPSLC7A5
Fluoride SCHEMBL28204481 0.98 ALPI (0.59) ALPIPKMPTGS1XIAPSLC7A5
Hydrochloric Acid SCHEMBL27531497 0.98 ALPI (0.59) ALPIPKMPTGS1XIAPSLC7A5
Hydrochloric Acid SCHEMBL27531496 0.98 ALPI (0.59) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL7864444 0.98 ALPI (0.59) ALPIPKMPTGS1XIAPSLC7A5
Hydrochloric Acid SCHEMBL839857 0.98 ALPI (0.59) ALPIPKMPTGS1XIAPSLC7A5
Hydrochloric Acid SCHEMBL1098660 0.98 ALPI (0.59) ALPIPKMPTGS1XIAPSLC7A5
Hydrochloric Acid SCHEMBL216055 0.98 ALPI (0.59) ALPIPKMPTGS1XIAPSLC7A5
Hydrochloric Acid SCHEMBL16223226 0.97 PKM (0.58) ALPIPKMPTGS1XIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118007135-A Corrosion inhibition method for inhibiting metal corrosion in sulfur-containing medium 福建理工大学 2024-05-10 — — CN claimed
CN-118007135-A Corrosion inhibition method for inhibiting metal corrosion in sulfur-containing medium 福建理工大学 2024-05-10 — — CN disclosed
EP-3015488-B1 PRODUCTION METHOD FOR POLYAMINO ACID TAKEDA PHARMACEUTICALS CO (JP) 2024-03-06 — — EP disclosed
CN-113845569-B Synthetic method of pasireotide intermediate 浙江湃肽生物有限公司南京分公司 2022-02-18 — — CN disclosed
CN-113845569-A Synthetic method of pasireotide intermediate 浙江湃肽生物有限公司南京分公司 2021-12-28 — — CN disclosed
CN-106316982-B Thiazine amide derivative and use thereof 中国人民解放军军事医学科学院毒物药物研究所 2020-08-14 — — CN disclosed
US-10669242-B2 Clostridium difficile toxin inhibitors Venenum Biodesign, LLC (US) 2020-06-02 — — US disclosed
US-10335417-B2 Thiazideamide derivative and use thereof INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA (CN) 2019-07-02 — — US disclosed
US-10336864-B2 Production method for poly(amino acid) TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-07-02 — — US disclosed
US-20190194147-A1 Novel Clostridium Difficile Toxin Inhibitors Venenum Biodesign, LLC (US) 2019-06-27 — — US disclosed
EP-0364016-A1 Polyphosphazene polymers and their preparation Stichting Biomaterials Science Center, VU, "BSC-VU" (NL) 1990-04-18 — — EP disclosed
WO-1990003389-A1 RENIN INHIBITORY PEPTIDES CONTAINING MALEAMIDE SUBSTITUENTS THE UPJOHN COMPANY (US) 1990-04-05 — — WO disclosed
WO-1988006187-A1 A PROCESS FOR ENZYMATIC PRODUCTION PRODUCTION OF DIPEPTIDES CARLSBERG BIOTECHNOLOGY LTD. A/S (DK) 1988-08-25 — — WO disclosed
EP-0278787-A1 A process for enzymatic production of dipeptides CARLBIOTECH LTD. A/S (DK) 1988-08-17 — — EP disclosed
US-4661629-A Separation of phenylalanine from phenylalanine ethyl ester THE STANDARD OIL COMPANY (US) 1987-04-28 — — US disclosed
US-4613691-A Preparation of amino acids from unsaturated hydantoins STAUFFER CHEMICAL COMPANY (US) 1986-09-23 — — US disclosed
EP-0177072-A2 Preparation of amino acids from unsaturated hydantoins STAUFFER CHEMICAL COMPANY (US) 1986-04-09 — — EP disclosed
US-4048305-A PHENYLALANINE, HISTIDINE DR. L. ZAMBELETTI S.P.A. (IT) 1977-09-13 — — US disclosed
US-3970700-A Racemization of optically active amines SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-07-20 — — US disclosed
US-3941831-A Resolution of alkyl esters of DL-phenylalanine G. D. SEARLE & CO. (US) 1976-03-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10335417-B2 Thiazideamide derivative and use thereof TREH, AQP4, TST ALPI 1975/4885PKM 1072/4885PTGS1 1938/4885
US-20190194147-A1 Novel Clostridium Difficile Toxin Inhibitors GABRA5, GABRA1, GABRA4 ALPI 153/4885PKM 3028/4885PTGS1 1653/4885
US-10336864-B2 Production method for poly(amino acid) PGA5, ENPEP, PARG ALPI 1763/4885PKM 634/4885PTGS1 412/4885
US-10669242-B2 Clostridium difficile toxin inhibitors GABRA5, GABRA1, GABBR2 ALPI 110/4885PKM 2796/4885PTGS1 1498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.