Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HRH2 | P25021 | 2/20 | 0.49 |
| ▸ | HRH1 | P35367 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7387252 | 1.00 | MAPK1 (0.51) | MAPK1ALDH1A1LMNAKMT2AHRH2 | |
| SCHEMBL6981597 | 0.85 | MAPK1 (0.52) | MAPK1ALDH1A1LMNAKMT2AHRH2 | |
| SCHEMBL7390948 | 0.85 | PABPC1 (0.61) | MAPK1KMT2AHRH2HRH1PABPC1 | |
| SCHEMBL7390953 | 0.85 | PABPC1 (0.61) | MAPK1KMT2AHRH2HRH1PABPC1 | |
| SCHEMBL7384526 | 0.82 | IGF1R (0.44) | KMT2AMEN1POLB | |
| SCHEMBL7384524 | 0.82 | IGF1R (0.44) | KMT2AMEN1POLB | |
| SCHEMBL7390924 | 0.82 | CACNA2D1 (0.49) | CACNA2D1CACNA1BCACNB1CACNA1CMGLL | |
| SCHEMBL7664035 | 0.82 | CACNA2D1 (0.49) | CACNA2D1CACNA1BCACNB1CACNA1CMGLL | |
| Hydrochloric Acid SCHEMBL7653866 | 0.81 | CACNA1B (0.48) | CACNA2D1CACNA1BCACNB1CACNA1CMGLL | |
| Hydrochloric Acid SCHEMBL7653878 | 0.81 | CACNA1B (0.48) | CACNA2D1CACNA1BCACNB1CACNA1CMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999055688-A1 | SUBSTITUTED DIARYLALKYL AMIDES AS CALCIUM CHANNEL ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1999-11-04 | — | — | WO | claimed |
| US-6458781-B1 | BLOCKERS CALCIUM CHANNEL ANTAGONISTS FOR STROKES, BRAIN DISORDERS | WARNER-LAMBERT COMPANY | 2002-10-01 | — | — | US | disclosed |
| WO-1999055688-A1 | SUBSTITUTED DIARYLALKYL AMIDES AS CALCIUM CHANNEL ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1999-11-04 | — | — | WO | disclosed |