Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.42 |
| ▸ | ACACB | O00763 | 3/20 | 0.42 |
| ▸ | ACACA | Q13085 | 3/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7385380 | 1.00 | DRD2 (0.42) | DRD2ACACBACACAITGB3ITGA2B | |
| SCHEMBL7385382 | 1.00 | DRD2 (0.42) | DRD2ACACBACACAITGB3ITGA2B | |
| SCHEMBL7387297 | 1.00 | DRD2 (0.42) | DRD2ACACBACACAITGB3ITGA2B | |
| SCHEMBL7389351 | 1.00 | DRD2 (0.42) | DRD2ACACBACACAITGB3ITGA2B | |
| SCHEMBL7385013 | 0.99 | DRD2 (0.43) | DRD2ACACBACACAITGB3ITGA2B | |
| SCHEMBL7387215 | 0.99 | DRD2 (0.43) | DRD2ACACBACACAITGB3ITGA2B | |
| SCHEMBL7385015 | 0.99 | DRD2 (0.43) | DRD2ACACBACACAITGB3ITGA2B | |
| SCHEMBL7381670 | 0.95 | DRD2 (0.43) | DRD2ACACBACACAITGB3ITGA2B | |
| SCHEMBL7381674 | 0.95 | DRD2 (0.43) | DRD2ACACBACACAITGB3ITGA2B | |
| SCHEMBL7385840 | 0.95 | DRD2 (0.43) | DRD2ACACBACACAITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0774460-A1 | BENZOIC ACID COMPOUND AND USE THEREOF AS MEDICINE | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-05-21 | — | — | EP | disclosed |