Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | KDM5A | P29375 | 4/20 | 0.45 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7377817 | 0.98 | MAPT (0.65) | MAPTKDM5APHF8KDM2AKDM4C | |
| SCHEMBL7382699 | 0.97 | MAPT (0.67) | MAPTKDM5APHF8KDM2AKDM4C | |
| SCHEMBL5695141 | 0.93 | MAPT (0.58) | MAPTKDM5APHF8KDM2AKDM4C | |
| SCHEMBL7171947 | 0.93 | MAPT (0.76) | MAPTKDM5APHF8KDM2AKDM4C | |
| SCHEMBL7378752 | 0.92 | MAPT (0.56) | MAPTKDM5APHF8KDM2AKDM4C | |
| SCHEMBL7376739 | 0.90 | MAPT (0.58) | MAPTKDM5APHF8KDM2AKDM4C | |
| SCHEMBL7385597 | 0.86 | MAPT (0.66) | MAPTKDM5APHF8KDM2AKDM4C | |
| SCHEMBL17867068 | 0.85 | MAPT (0.66) | MAPTKDM5APHF8KDM2AKDM4C | |
| SCHEMBL7385945 | 0.84 | MAPT (0.47) | MAPTKDM5APHF8KDM2AKDM4C | |
| SCHEMBL7380129 | 0.83 | MAPT (0.46) | MAPTKDM5APHF8KDM2AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192125-A2 | MONO- AND DISUBSTITUTED 3-PROPYL GAMMA-AMINOBUTYRIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000076958-A2 | MONO- AND DISUBSTITUTED 3-PROPYL GAMMA-AMINOBUTYRIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2000-12-21 | — | — | WO | disclosed |