Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
| ▸ | GABRE | P78334 | 2/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5695141 | 0.93 | MAPT (0.58) | MAPTKDM5AKDM4CPHF8KDM2A | |
| SCHEMBL7376739 | 0.93 | MAPT (0.58) | MAPTKDM5AKDM4CPHF8KDM2A | |
| SCHEMBL7171947 | 0.93 | MAPT (0.76) | MAPTKDM5AKDM7AKDM4CPHF8 | |
| SCHEMBL7378752 | 0.91 | MAPT (0.56) | MAPTKDM5AKDM4CPHF8KDM2A | |
| SCHEMBL7387306 | 0.86 | MAPT (0.67) | MAPTKDM5AKDM7AKDM4CPHF8 | |
| SCHEMBL7382699 | 0.86 | MAPT (0.67) | MAPTKDM5AKDM7AKDM4CPHF8 | |
| SCHEMBL7377817 | 0.84 | MAPT (0.65) | MAPTKDM5AKDM4CPHF8KDM2A | |
| SCHEMBL7380671 | 0.83 | MAPT (0.54) | MAPTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL14360701 | 0.82 | LMNA (0.53) | MAPTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL4983489 | 0.80 | MAPT (0.59) | MAPTKDM5AKDM4CPHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192125-A2 | MONO- AND DISUBSTITUTED 3-PROPYL GAMMA-AMINOBUTYRIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000076958-A2 | MONO- AND DISUBSTITUTED 3-PROPYL GAMMA-AMINOBUTYRIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2000-12-21 | — | — | WO | disclosed |