SCHEMBL738764

SCHEMBL738764

CS(=O)(=O)OCC(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21618302 0.84 KDM4E (0.36)
SCHEMBL2635414 0.81
SCHEMBL6302119 0.79
SCHEMBL10254994 0.79 CA1 (0.41)
SCHEMBL18926178 0.77 KDM4E (0.34)
SCHEMBL25238239 0.77 CA1 (0.31)
SCHEMBL20267770 0.76 ALDH1A1 (0.42)
SCHEMBL776575 0.74
SCHEMBL5990289 0.74 CA1 (0.59)
SCHEMBL28386059 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240363910-A1 ELECTROCHEMICAL DEVICE AND ELECTRONIC DEVICE CONTAINING SAME NINGDE AMPEREX TECHNOLOGY LIMITED (CN) 2024-10-31 US claimed
WO-2023130423-A1 ELECTROCHEMICAL DEVICE AND ELECTRONIC DEVICE COMPRISING SAME 宁德新能源科技有限公司 2023-07-13 WO claimed
CN-109574884-A A kind of preparation method of 2- (2,2- difluoroethoxy) -6- trifluoromethyl propyl thioether 淮安国瑞化工有限公司 2019-04-05 CN claimed
CN-105294520-A 2-(2 ', 2'-difluoro-ethoxy)-6-trifluoromethyl-phenylpropyl sulfur ether synthesis process DALIAN JOIN KING BIOCHEM TECH CO LTD 2016-02-03 CN claimed
US-20090105289-A1 11beta-hydroxysteroid dehydrogenase type 1 active spiro compounds NOVO NORDISK A/S (DK) 2009-04-23 US claimed
JP-7145099-A None JP disclosed
EP-4739670-A1 MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE F. Hoffmann-La Roche AG (CH) 2026-05-13 EP disclosed
WO-2025226861-A1 CYCLIN INHIBITORS CIRCLE PHARMA, INC. (US) 2025-10-30 WO disclosed
US-20250320189-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS UNIV LEUVEN KATH (BE) 2025-10-16 US disclosed
EP-4532479-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP disclosed
CN-119403794-A Novel derivatives for the treatment of TRPM3 mediated disorders 勒芬天主教大学 2025-02-07 CN disclosed
WO-2025012057-A1 MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE F. HOFFMANN-LA ROCHE AG (CH) 2025-01-16 WO disclosed
CN-1487919-A Novel mandelic acid derivatives and their use as thrombin inhibitors 2004-04-07 CN disclosed
US-20040019033-A1 Mandelic acid derivatives and their use as throbin inhibitors ASTRAZENECA AB (SE) 2004-01-29 US disclosed
EP-1373240-A2 RETINOID X RECEPTOR MODULATORS ELI LILLY AND COMPANY (US) 2004-01-02 EP disclosed
WO-2003101956-A1 PHARMACEUTICAL COMBINATION ASTRAZENECA AB (SE) 2003-12-11 WO disclosed
EP-1347955-A1 NEW MANDELIC ACID DERIVATIVES AND THEIR USE AS THROBIN INHIBITORS AstraZeneca AB (SE) 2003-10-01 EP disclosed
WO-2002071827-A2 RETINOID X RECEPTOR MODULATORS ELI LILLY AND COMPANY (US) 2002-09-19 WO disclosed
WO-2002044145-A1 NEW MANDELIC ACID DERIVATIVES AND THEIR USE AS THROBIN INHIBITORS ASTRAZENECA AB (SE) 2002-06-06 WO disclosed
JP-H07145099-A BENZENE DERIVATIVE AND LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH 1995-06-06 JP disclosed