Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7393443 | 0.88 | CACNA1B (0.51) | NPC1ALDH1A1MAPTMAPK1HTT | |
| SCHEMBL7036969 | 0.87 | MEN1 (0.46) | CACNA1BMEN1KMT2AGPR119 | |
| SCHEMBL7429335 | 0.86 | CACNA1B (0.52) | NPC1ALDH1A1MAPTMAPK1HTT | |
| SCHEMBL7037543 | 0.84 | CACNA1B (0.60) | CACNA1BMEN1KMT2AGPR119 | |
| SCHEMBL7385841 | 0.84 | CACNA1B (0.51) | CACNA1BMEN1KMT2AGPR119 | |
| SCHEMBL7424188 | 0.81 | CACNA1B (0.58) | CACNA1B | |
| SCHEMBL7383571 | 0.81 | CACNA1B (0.58) | CACNA1B | |
| SCHEMBL7040340 | 0.81 | CACNA1B (0.69) | CACNA1BMEN1KMT2A | |
| SCHEMBL7421570 | 0.80 | CACNA1B (0.43) | ALDH1A1CACNA1B | |
| SCHEMBL10159468 | 0.79 | MEN1 (0.62) | ALDH1A1MEN1KMT2AGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251919-B1 | ADMINISTERING ANILINE DERIVATIVE FOR THERAPY OF PAIN | WARNER-LAMBERT | 2001-06-26 | — | — | US | disclosed |
| WO-1999043658-A1 | HETEROCYCLIC SUBSTITUTED ANILINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1999-09-02 | — | — | WO | disclosed |