Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 10/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7383571 | 0.86 | CACNA1B (0.58) | CACNA1B | |
| SCHEMBL7388010 | 0.86 | NPC1 (0.54) | CACNA1BALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL7424188 | 0.86 | CACNA1B (0.58) | CACNA1B | |
| SCHEMBL7421570 | 0.84 | CACNA1B (0.43) | CACNA1BALDH1A1 | |
| SCHEMBL7390792 | 0.81 | CACNA1B (0.42) | CACNA1B | |
| SCHEMBL7390389 | 0.81 | CACNA1B (0.45) | CACNA1B | |
| SCHEMBL7391056 | 0.81 | CACNA1B (0.43) | CACNA1BALDH1A1 | |
| SCHEMBL7380663 | 0.81 | CACNA1B (0.45) | CACNA1BALDH1A1 | |
| SCHEMBL7387300 | 0.79 | CACNA1B (0.60) | CACNA1B | |
| SCHEMBL7390855 | 0.79 | CACNA1B (0.44) | CACNA1BOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999043658-A1 | HETEROCYCLIC SUBSTITUTED ANILINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1999-09-02 | — | — | WO | disclosed |