Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | CCR3 | P51677 | 1/20 | 0.60 |
| ▸ | DRD2 | P14416 | 4/20 | 0.58 |
| ▸ | DRD4 | P21917 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 4/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7386299 | 0.96 | CCR3 (0.65) | ALDH1A1SMN1; SMN2KDM4ECCR3DRD2 | |
| SCHEMBL27675265 | 0.94 | CCR3 (0.64) | ALDH1A1SMN1; SMN2KDM4ECCR3DRD2 | |
| SCHEMBL7381097 | 0.94 | CCR3 (0.64) | ALDH1A1SMN1; SMN2KDM4ECCR3DRD2 | |
| SCHEMBL7391346 | 0.94 | CCR3 (0.64) | ALDH1A1SMN1; SMN2KDM4ECCR3DRD2 | |
| SCHEMBL7388218 | 0.92 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2KDM4ECCR3DRD2 | |
| SCHEMBL10720845 | 0.91 | ALDH1A1 (0.76) | ALDH1A1SMN1; SMN2KDM4ECCR3DRD2 | |
| SCHEMBL1384427 | 0.88 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2KDM4ECCR3DRD2 | |
| SCHEMBL10723691 | 0.88 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2KDM4ECCR3DRD2 | |
| SCHEMBL7392283 | 0.87 | CCR3 (0.59) | ALDH1A1SMN1; SMN2KDM4ECCR3DRD2 | |
| SCHEMBL5474202 | 0.87 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2KDM4ECCR3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0774460-A1 | BENZOIC ACID COMPOUND AND USE THEREOF AS MEDICINE | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-05-21 | — | — | EP | disclosed |