Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.63 |
| ▸ | CTSD | P07339 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7386714 | 0.94 | REN (0.64) | RENCTSD | |
| SCHEMBL7394869 | 0.93 | REN (0.63) | RENCTSD | |
| SCHEMBL7396325 | 0.89 | REN (0.73) | RENCTSD | |
| SCHEMBL7391114 | 0.88 | REN (0.65) | RENCTSD | |
| SCHEMBL7392288 | 0.87 | REN (0.82) | RENCTSD | |
| SCHEMBL7390992 | 0.86 | REN (0.77) | RENCTSD | |
| SCHEMBL7391405 | 0.86 | REN (0.72) | RENCTSD | |
| SCHEMBL7396084 | 0.86 | REN (0.67) | RENCTSD | |
| SCHEMBL7390864 | 0.84 | REN (0.50) | RENCTSD | |
| SCHEMBL7396421 | 0.80 | REN (0.54) | RENCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589445-A1 | Renin Inhibiting N-(2-Amino-2-oxoethyl)Butanediamide Derivatives | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1994-03-30 | — | — | EP | claimed |