Hexane

Hexane

SCHEMBL7388183

CCCCCC.CCCO.ClC(Cl)Cl

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.59
TSHR P16473 5/20 0.56
LMNA P02545 4/20 0.56
ALDH1A1 P00352 4/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
HSD17B10 Q99714 1/20 0.56
THRB P10828 2/20 0.44
DNM1 Q05193 2/20 0.40
HTT P42858 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexane SCHEMBL28322647 0.90 ALDH1A1 (0.69) SMN1; SMN2TSHRLMNAALDH1A1MEN1
1-Pentanol SCHEMBL11280714 0.90 SMN1; SMN2 (0.75) SMN1; SMN2TSHRLMNAALDH1A1MEN1
Hexane SCHEMBL6745539 0.90 SMN1; SMN2 (0.53) SMN1; SMN2TSHRLMNAALDH1A1MEN1
Propanol SCHEMBL1433302 0.89
1-Pentanol SCHEMBL28908456 0.88 SMN1; SMN2 (0.71) SMN1; SMN2TSHRLMNAALDH1A1MEN1
Hexane SCHEMBL28543105 0.88 ALDH1A1 (0.65) SMN1; SMN2TSHRLMNAALDH1A1MEN1
Nonanol SCHEMBL12275209 0.88 ALDH1A1 (0.77) SMN1; SMN2TSHRLMNAALDH1A1MEN1
1-Hexanol SCHEMBL9796428 0.88 ALDH1A1 (0.77) SMN1; SMN2TSHRLMNAALDH1A1MEN1
1-Heptanol SCHEMBL6171012 0.88 ALDH1A1 (0.77) SMN1; SMN2TSHRLMNAALDH1A1MEN1
Octanol SCHEMBL467972 0.88 ALDH1A1 (0.77) SMN1; SMN2TSHRLMNAALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5389612-A Treating infections caused by clostridium histolyticum and pseudomonas aeruginosa; enzyme inhibitors COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1995-02-14 US disclosed