Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 4/20 | 0.58 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.58 |
| ▸ | OXTR | P30559 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5739732 | 0.91 | AVPR2 (0.54) | AVPR2AVPR1A | |
| SCHEMBL29385181 | 0.87 | AVPR2 (0.77) | AVPR2AVPR1AOXTR | |
| SCHEMBL5738957 | 0.87 | AVPR2 (0.77) | AVPR2AVPR1AOXTR | |
| SCHEMBL7368892 | 0.82 | AVPR2 (0.56) | AVPR2AVPR1A | |
| SCHEMBL5739209 | 0.82 | AVPR2 (0.59) | AVPR2AVPR1AOXTR | |
| SCHEMBL7339651 | 0.80 | AVPR2 (0.51) | AVPR2AVPR1AOXTR | |
| SCHEMBL7367681 | 0.79 | AVPR2 (0.66) | AVPR2AVPR1A | |
| SCHEMBL7334645 | 0.78 | AVPR2 (0.49) | AVPR2AVPR1A | |
| SCHEMBL7334536 | 0.78 | AVPR2 (0.51) | AVPR2AVPR1A | |
| SCHEMBL7335243 | 0.77 | AVPR2 (0.48) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612334-A | Tricyclic benzazepine vasopressin antagonists | AMERICAN CYANAMID COMPANY (US) | 1997-03-18 | — | — | US | disclosed |
| WO-1996022293-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |
| US-5536718-A | Tricyclic benzazepine vasopressin antagonists | AMERICAN CYANAMID COMPANY (US) | 1996-07-16 | — | — | US | disclosed |