SCHEMBL29385181

SCHEMBL29385181

Cc1ccc(F)cc1C(=O)Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cn1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AVPR2 P30518 5/20 0.77
AVPR1A P37288 5/20 0.77
OXTR P30559 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5738957 1.00 AVPR2 (0.77) AVPR2AVPR1AOXTR
SCHEMBL5739209 0.88 AVPR2 (0.59) AVPR2AVPR1AOXTR
SCHEMBL7388286 0.87 AVPR2 (0.58) AVPR2AVPR1AOXTR
SCHEMBL7335324 0.87 AVPR2 (1.00) AVPR2AVPR1AOXTR
SCHEMBL7368892 0.85 AVPR2 (0.56) AVPR2AVPR1A
SCHEMBL5738696 0.84
SCHEMBL5738960 0.84
SCHEMBL8317862 0.84 AVPR2 (1.00) AVPR2AVPR1AOXTR
SCHEMBL5739732 0.84 AVPR2 (0.54) AVPR2AVPR1A
Hydrochloric Acid SCHEMBL5739031 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3737233-B1 GROWTH FACTOR OTIC FORMULATIONS DOMPE FARM SPA (IT) 2025-03-19 EP disclosed
US-20240358634-A1 AURIS FORMULATIONS FOR TREATING OTIC DISEASES AND CONDITIONS DOMPÉ FARMACEUTICI S.P.A. (IT) 2024-10-31 US disclosed
US-11969501-B2 Auris formulations for treating otic diseases and conditions DOMPÉ FARMACEUTICI S.P.A. (IT) 2024-04-30 US disclosed
US-11918653-B2 Triglyceride otic formulations and uses thereof DOMPÉ FARMACEUTICI S.P.A. (IT) 2024-03-05 US disclosed
US-20230190642-A1 GROWTH FACTOR OTIC FORMULATIONS DOMPÉ FARMACEUTICI S.P.A. (IT) 2023-06-22 US disclosed
CN-115869389-A Growth factor ear preparation 奥德纳米有限公司 2023-03-31 CN disclosed
US-11389534-B2 Methods of treating a subject for a condition PALO ALTO INVESTORS (US) 2022-07-19 US disclosed
US-20220040095-A1 AURIS FORMULATIONS FOR TREATING OTIC DISEASES AND CONDITIONS DOMPÉ FARMACEUTICI S.P.A. (IT) 2022-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230190642-A1 GROWTH FACTOR OTIC FORMULATIONS AREG, HDGF, NGF AVPR2 911/4885AVPR1A 968/4885OXTR 145/4885
US-11918653-B2 Triglyceride otic formulations and uses thereof CETP, LIPA, APOB AVPR2 3337/4885AVPR1A 3673/4885OXTR 571/4885
US-20240358634-A1 AURIS FORMULATIONS FOR TREATING OTIC DISEASES AND CONDITIONS OTC, AQP4, SLC26A4 AVPR2 1018/4885AVPR1A 1282/4885OXTR 663/4885
US-20220040095-A1 AURIS FORMULATIONS FOR TREATING OTIC DISEASES AND CONDITIONS OTC, AQP4, SLC26A4 AVPR2 1018/4885AVPR1A 1282/4885OXTR 663/4885
US-11969501-B2 Auris formulations for treating otic diseases and conditions OTC, AQP4, SLC26A4 AVPR2 1018/4885AVPR1A 1282/4885OXTR 663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.