Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.59 |
| ▸ | ITGAV | P06756 | 6/20 | 0.49 |
| ▸ | ITGB5 | P18084 | 4/20 | 0.49 |
| ▸ | ITGB6 | P18564 | 4/20 | 0.49 |
| ▸ | ITGB8 | P26012 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | CTSA | P10619 | 2/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7384204 | 0.94 | ITGB3 (0.67) | ITGB3ITGA2BITGAVITGB5ITGB6 | |
| SCHEMBL7380918 | 0.94 | ITGB3 (0.60) | ITGB3ITGA2BITGAVITGB5ITGB6 | |
| SCHEMBL7390056 | 0.90 | ITGB3 (0.56) | ITGB3ITGA2BITGAVITGB5ITGB6 | |
| SCHEMBL7383936 | 0.89 | ITGB3 (0.56) | ITGB3ITGA2BITGAVITGB5ITGB6 | |
| SCHEMBL7385748 | 0.89 | ITGB3 (0.55) | ITGB3ITGA2BITGAVITGB5ITGB6 | |
| SCHEMBL7385778 | 0.89 | ITGB3 (0.60) | ITGB3ITGA2BITGAVITGB5ITGB6 | |
| SCHEMBL7392702 | 0.89 | ITGB3 (0.55) | ITGB3ITGA2BITGAVITGB5ITGB6 | |
| SCHEMBL7388743 | 0.89 | ITGB3 (0.55) | ITGB3ITGA2BITGAVITGB5ITGB6 | |
| SCHEMBL9710599 | 0.88 | ITGB3 (0.57) | ITGB3ITGA2BITGAVITGB5ITGB6 | |
| SCHEMBL7389153 | 0.87 | ITGB3 (0.54) | ITGB3ITGA2BITGAVITGB5ITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5220050-A | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G. D. SEARLE & CO. (US) | 1993-06-15 | — | — | US | disclosed |
| WO-1992020705-A1 | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1992-11-26 | — | — | WO | disclosed |
| EP-0513810-A1 | Peptide mimetic compounds useful as platelet aggregation inhibitors | G.D. Searle & Co. (US) | 1992-11-19 | — | — | EP | disclosed |