Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30826996 | 0.92 | TBXAS1 (0.50) | TBXAS1PRSS1 | |
| SCHEMBL7088226 | 0.92 | TBXAS1 (0.50) | TBXAS1PRSS1KCNA3HRH1CCR3 | |
| SCHEMBL22120309 | 0.92 | TBXAS1 (0.50) | TBXAS1PRSS1 | |
| SCHEMBL5988834 | 0.92 | TBXAS1 (0.50) | TBXAS1PRSS1 | |
| SCHEMBL6957299 | 0.92 | TSHR (0.59) | TBXAS1 | |
| SCHEMBL25168671 | 0.92 | TSHR (0.59) | TBXAS1 | |
| SCHEMBL14034743 | 0.92 | TSHR (0.59) | TBXAS1 | |
| SCHEMBL11033727 | 0.92 | TBXAS1 (0.50) | TBXAS1PRSS1 | |
| SCHEMBL6960220 | 0.92 | TSHR (0.59) | TBXAS1 | |
| SCHEMBL690259 | 0.91 | TBXAS1 (0.52) | TBXAS1PRSS1KCNA3HRH1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221914-B1 | ANTIINFLAMMATORY AGENTS | ARRAY BIOPHARMA INC. | 2001-04-24 | — | — | US | disclosed |
| WO-1999024395-A1 | COMPOUNDS WHICH INHIBIT TRYPTASE ACTIVITY | ARRAY BIOPHARMA, INC. (US) | 1999-05-20 | — | — | WO | disclosed |