Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 14/20 | 0.51 |
| ▸ | CTSD | P07339 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7390445 | 0.91 | REN (0.51) | RENCTSD | |
| SCHEMBL7391351 | 0.90 | REN (0.50) | RENCTSDL3MBTL1ALDH1A1LMNA | |
| SCHEMBL7391896 | 0.89 | REN (0.66) | RENCTSD | |
| SCHEMBL7390896 | 0.89 | REN (0.66) | RENCTSD | |
| SCHEMBL7391664 | 0.89 | REN (0.66) | RENCTSD | |
| SCHEMBL7385470 | 0.87 | REN (0.46) | RENCTSDMAPK1SMN1; SMN2HPGD | |
| SCHEMBL7384225 | 0.84 | REN (0.52) | RENCTSDMAPK1SMN1; SMN2HPGD | |
| SCHEMBL7392956 | 0.83 | REN (0.62) | RENCTSD | |
| SCHEMBL7394858 | 0.83 | REN (0.46) | RENCTSDMAPK1SMN1; SMN2HPGD | |
| SCHEMBL7383975 | 0.82 | REN (0.37) | RENCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589445-B1 | Renin Inhibiting N-(2-Amino-2-oxoethyl)Butanediamide Derivatives | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1997-01-15 | — | — | EP | claimed |