Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 19/20 | 0.80 |
| ▸ | ACHE | P22303 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | HTR3A | P46098 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351188 | 0.89 | HTR4 (1.00) | HTR4ACHEMEN1ALDH1A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL7355174 | 0.89 | HTR4 (0.96) | HTR4ACHEMEN1ALDH1A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL194956 | 0.88 | HTR4 (0.98) | HTR4ACHEMEN1ALDH1A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL7354962 | 0.88 | HTR4 (0.98) | HTR4ACHEMEN1ALDH1A1CYP2D6 | |
| SCHEMBL7350061 | 0.86 | HTR4 (0.78) | HTR4ACHEMEN1ALDH1A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL7359056 | 0.85 | HTR4 (0.95) | HTR4ACHEMEN1ALDH1A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL7358849 | 0.85 | HTR4 (0.77) | HTR4ACHEMEN1ALDH1A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL7353346 | 0.85 | HTR4 (0.77) | HTR4ACHEMEN1ALDH1A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL7349823 | 0.85 | HTR4 (0.77) | HTR4ACHEMEN1ALDH1A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL7357853 | 0.84 | HTR4 (0.98) | HTR4ACHEMEN1ALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0873990-A1 | BENZOIC ACID COMPOUNDS AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-10-28 | — | — | EP | disclosed |