Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | GMNN | O75496 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7391883 | 0.98 | PTPN1 (0.65) | PTPN1ALDH1A1MAPTLMNAHPGD | |
| SCHEMBL3381314 | 0.85 | ALDH1A1 (0.59) | PTPN1ALDH1A1MAPTLMNAHPGD | |
| SCHEMBL27819105 | 0.83 | MAPT (0.58) | PTPN1ALDH1A1MAPTLMNAHPGD | |
| SCHEMBL3382572 | 0.83 | MAPT (0.58) | PTPN1ALDH1A1MAPTLMNAHPGD | |
| SCHEMBL1844647 | 0.83 | ALDH1A1 (0.58) | PTPN1ALDH1A1MAPTLMNAHPGD | |
| SCHEMBL9857065 | 0.83 | MEN1 (0.62) | PTPN1ALDH1A1MAPTLMNAHPGD | |
| SCHEMBL18156077 | 0.83 | ALDH1A1 (0.58) | PTPN1ALDH1A1MAPTLMNAHPGD | |
| SCHEMBL7176337 | 0.83 | ALDH1A1 (0.58) | PTPN1ALDH1A1MAPTLMNAHPGD | |
| SCHEMBL27561707 | 0.83 | ALDH1A1 (0.58) | PTPN1ALDH1A1MAPTLMNAHPGD | |
| SCHEMBL14652459 | 0.82 | ALDH1A1 (0.56) | PTPN1ALDH1A1MAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0873990-A1 | BENZOIC ACID COMPOUNDS AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-10-28 | — | — | EP | disclosed |