Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 19/20 | 0.61 |
| ▸ | DRD3 | P35462 | 19/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389679 | 1.00 | DRD2 (0.61) | DRD2DRD3SIGMAR1 | |
| SCHEMBL7389683 | 1.00 | DRD2 (0.61) | DRD2DRD3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7681069 | 0.99 | DRD2 (0.60) | DRD2DRD3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7681068 | 0.99 | DRD2 (0.60) | DRD2DRD3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7681063 | 0.99 | DRD2 (0.60) | DRD2DRD3SIGMAR1 | |
| SCHEMBL7395930 | 0.95 | DRD2 (0.59) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7682905 | 0.94 | DRD2 (0.58) | DRD2DRD3 | |
| SCHEMBL7395997 | 0.94 | DRD2 (0.58) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7682902 | 0.94 | DRD2 (0.58) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7687313 | 0.93 | DRD2 (0.57) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0887350-B1 | Chromene derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-08-22 | — | — | EP | disclosed |
| EP-0887350-A1 | Chromene derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-12-30 | — | — | EP | disclosed |