Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389831 | 1.00 | ALDH1A1 (0.44) | ALDH1A1GAABTKSMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7389071 | 0.84 | ALDH1A1 (0.45) | ALDH1A1GAABTKSMN1; SMN2L3MBTL1 | |
| SCHEMBL7394211 | 0.81 | MAPT (0.41) | ALDH1A1GAABTKMAPTHSD17B10 | |
| SCHEMBL7394208 | 0.81 | MAPT (0.41) | ALDH1A1GAABTKMAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL7391497 | 0.75 | KHK (0.39) | BTKHRH3 | |
| Hydrochloric Acid SCHEMBL7390541 | 0.74 | HRH3 (0.43) | ALDH1A1GAABTKMAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL8413942 | 0.74 | HRH3 (0.43) | ALDH1A1GAABTKMAPTHSD17B10 | |
| SCHEMBL7390283 | 0.73 | S1PR5 (0.42) | POLBHPGDHRH3 | |
| SCHEMBL7390279 | 0.73 | S1PR5 (0.42) | POLBHPGDHRH3 | |
| Hydrochloric Acid SCHEMBL7394016 | 0.72 | HRH3 (0.42) | POLBHPGDHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587134-A2 | Cyclic urea derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1994-03-16 | — | — | EP | disclosed |