Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 12/20 | 0.78 |
| ▸ | DRD2 | P14416 | 2/20 | 0.67 |
| ▸ | DRD4 | P21917 | 2/20 | 0.67 |
| ▸ | DRD3 | P35462 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389801 | 0.97 | HTR4 (0.77) | HTR4DRD2DRD4DRD3 | |
| SCHEMBL7385451 | 0.96 | HTR4 (0.76) | HTR4 | |
| SCHEMBL7387877 | 0.96 | HTR4 (0.76) | HTR4 | |
| SCHEMBL506210 | 0.92 | HTR4 (0.78) | HTR4DRD2DRD4DRD3 | |
| SCHEMBL9021817 | 0.90 | HTR4 (0.76) | HTR4DRD2DRD4DRD3 | |
| SCHEMBL7389932 | 0.89 | HTR4 (0.73) | HTR4 | |
| SCHEMBL7392142 | 0.88 | HTR4 (0.72) | HTR4DRD2DRD4DRD3 | |
| SCHEMBL725807 | 0.88 | HTR4 (1.00) | HTR4DRD2DRD4DRD3 | |
| SCHEMBL14827422 | 0.88 | HTR4 (0.75) | HTR4DRD2DRD4DRD3 | |
| SCHEMBL9021907 | 0.87 | HTR4 (0.71) | HTR4DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0873990-A1 | BENZOIC ACID COMPOUNDS AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-10-28 | — | — | EP | disclosed |
| EP-0774460-A1 | BENZOIC ACID COMPOUND AND USE THEREOF AS MEDICINE | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-05-21 | — | — | EP | disclosed |