Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7386042 | 0.87 | HTR3A (0.75) | SOS1HTR3A | |
| SCHEMBL14498813 | 0.87 | SOS1 (1.00) | SOS1HTR3A | |
| SCHEMBL7393070 | 0.86 | HTR3A (0.73) | SOS1HTR3A | |
| SCHEMBL7384368 | 0.86 | HTR3A (0.74) | SOS1HTR3A | |
| Lerisetron SCHEMBL30669539 | 0.85 | HTR3A (1.00) | SOS1HTR3A | |
| Lerisetron SCHEMBL141124 | 0.85 | HTR3A (1.00) | SOS1HTR3A | |
| Lerisetron SCHEMBL29040939 | 0.84 | HTR3A (0.97) | SOS1HTR3A | |
| SCHEMBL7395580 | 0.83 | SOS1 (0.76) | SOS1HTR3A | |
| SCHEMBL7398859 | 0.81 | HTR3A (0.66) | SOS1HTR3A | |
| SCHEMBL14498818 | 0.79 | HTR3A (0.73) | SOS1HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0628549-B1 | New 1-phenylmethyl benzimidazole piperazine derivatives | ESPANOLA DE PRODUCTOS FAB (ES) | 2000-12-06 | — | — | EP | claimed |
| EP-0628549-A1 | New 1-phenylmethyl benzimidazole piperazine derivatives | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) (ES) | 1994-12-14 | — | — | EP | claimed |
| US-7235538-B2 | Heterocyclic compounds, which are inhibitors of the enzyme DPP-IV | NOVO NORDISK A/S (DK) | 2007-06-26 | — | — | US | disclosed |
| US-7235538-B2 | Heterocyclic compounds, which are inhibitors of the enzyme DPP-IV | NOVO NORDISK A/S (DK) | 2007-06-26 | — | — | US | disclosed |
| EP-0628549-B1 | New 1-phenylmethyl benzimidazole piperazine derivatives | ESPANOLA DE PRODUCTOS FAB (ES) | 2000-12-06 | — | — | EP | disclosed |
| US-5672604-A | SEROTONIN RECEPTOR ANTAGONISTS | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS (FAES) (ES) | 1997-09-30 | — | — | US | disclosed |
| EP-0628549-A1 | New 1-phenylmethyl benzimidazole piperazine derivatives | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) (ES) | 1994-12-14 | — | — | EP | disclosed |