Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7391018 | 0.90 | GPR119 (0.40) | GPR119KDM4EALDH1A1GLAHPGD | |
| SCHEMBL8470397 | 0.84 | GPR119 (0.50) | GPR119ALKCETP | |
| SCHEMBL7387156 | 0.82 | GPR119 (0.48) | GPR119ALKHPGDF10CETP | |
| SCHEMBL8469683 | 0.81 | GPR119 (0.57) | GPR119ALKCETP | |
| SCHEMBL7389406 | 0.80 | GPR119 (0.46) | GPR119ALKF10CETPPIK3CD | |
| SCHEMBL7389408 | 0.80 | GPR119 (0.46) | GPR119ALKCETPPIK3CDPIK3CA | |
| SCHEMBL8469556 | 0.79 | GPR119 (0.51) | GPR119ALKCETP | |
| SCHEMBL7382020 | 0.79 | CLK1 (0.40) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7390133 | 0.76 | GPR119 (0.50) | GPR119ALKCETPBTK | |
| SCHEMBL7390135 | 0.76 | GPR119 (0.50) | GPR119ALKCETPBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5620991-A | ANTICOAGULANTS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| US-5576343-A | ANTICOAGULANTS; BLOOD-COAGULATION FACTOR X INHIBITORS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0540051-B1 | Aromatic amidine derivatives and salts thereof | DAIICHI SEIYAKU CO (JP) | 1996-04-03 | — | — | EP | disclosed |
| EP-0540051-A1 | Aromatic amidine derivatives and salts thereof | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-05-05 | — | — | EP | disclosed |