Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 16/20 | 0.68 |
| ▸ | DRD2 | P14416 | 2/20 | 0.67 |
| ▸ | DRD4 | P21917 | 2/20 | 0.67 |
| ▸ | DRD3 | P35462 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7383008 | 1.00 | HTR4 (0.68) | HTR4DRD2DRD4DRD3 | |
| SCHEMBL7383377 | 1.00 | HTR4 (0.68) | HTR4DRD2DRD4DRD3 | |
| SCHEMBL7389673 | 0.99 | HTR4 (0.69) | HTR4DRD2DRD4DRD3 | |
| SCHEMBL7391671 | 0.97 | HTR4 (0.69) | HTR4DRD2DRD4DRD3 | |
| SCHEMBL7391277 | 0.93 | HTR4 (0.67) | HTR4DRD2DRD4DRD3 | |
| SCHEMBL7388674 | 0.93 | HTR4 (0.67) | HTR4DRD2DRD4DRD3 | |
| SCHEMBL7425183 | 0.93 | HTR4 (0.65) | HTR4DRD2DRD4DRD3 | |
| SCHEMBL7389346 | 0.93 | HTR4 (0.72) | HTR4DRD2DRD4DRD3 | |
| SCHEMBL7386832 | 0.93 | HTR4 (0.69) | HTR4DRD2DRD4DRD3 | |
| SCHEMBL7391606 | 0.93 | HTR4 (0.66) | HTR4DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | claimed |
| EP-0873990-A1 | BENZOIC ACID COMPOUNDS AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-10-28 | — | — | EP | claimed |
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0873990-A1 | BENZOIC ACID COMPOUNDS AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-10-28 | — | — | EP | disclosed |