SCHEMBL739114

SCHEMBL739114

CCCCCCCCCCCCCCCCCCCCCC(=O)CCCNCCCO

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 0.53
▸ MAPT P10636 1/20 0.53
▸ HAO1 Q9UJM8 1/20 0.48
▸ NAAA Q02083 1/20 0.47
▸ CES2 O00748 3/20 0.45
▸ CES1 P23141 3/20 0.45
▸ ALDH1A1 P00352 3/20 0.44
▸ TSHR P16473 3/20 0.44
▸ LMNA P02545 2/20 0.44
▸ HSD17B10 Q99714 1/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ FAAH O00519 1/20 0.44
▸ HSP90AA1 P07900 1/20 0.44
▸ SLC22A6 Q4U2R8 1/20 0.43
▸ SLC22A8 Q8TCC7 1/20 0.43
▸ GPR84 Q9NQS5 1/20 0.43
▸ PPARG P37231 1/20 0.43
▸ PPARD Q03181 1/20 0.43
▸ PPARA Q07869 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL119158 1.00 KMT2A (0.53) KMT2AMAPTHAO1NAAACES2
SCHEMBL115930 1.00 KMT2A (0.53) KMT2AMAPTHAO1NAAACES2
Ethylene Glycol SCHEMBL26618261 0.94 KMT2A (0.55) KMT2AMAPTHAO1NAAACES2
Ethylene Glycol SCHEMBL26618281 0.94 KMT2A (0.55) KMT2AMAPTHAO1NAAACES2
Ethylene Glycol SCHEMBL26618254 0.94 KMT2A (0.55) KMT2AMAPTHAO1NAAACES2
SCHEMBL116811 0.92 MAPT (0.53) KMT2AMAPTHAO1NAAACES2
SCHEMBL117852 0.92 MAPT (0.53) KMT2AMAPTHAO1NAAACES2
SCHEMBL739427 0.92 MAPT (0.53) KMT2AMAPTHAO1NAAACES2
SCHEMBL29174023 0.90 KMT2A (0.59) KMT2AMAPTHAO1CES2CES1
SCHEMBL22894128 0.90 MAPT (0.59) KMT2AMAPTHAO1CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2658508-B2 TWO-PART HAIR COLOURING COMPOSITION KAO GERMANY GMBH (DE) 2024-06-19 — — EP disclosed
EP-2658508-B1 TWO-PART HAIR COLOURING COMPOSITION KAO GERMANY GMBH (DE) 2021-06-16 — — EP disclosed
EP-2560606-B1 COLOURING COMPOSITION KAO GERMANY GMBH (DE) 2017-08-23 — — EP disclosed
EP-2560608-B1 COLOURING COMPOSITION KAO GERMANY GMBH (DE) 2017-04-05 — — EP disclosed
EP-2346481-B1 COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR KAO GERMANY GMBH (DE) 2016-08-31 — — EP disclosed
EP-2377513-B1 Colouring composition KAO GERMANY GMBH (DE) 2016-03-30 — — EP disclosed
EP-2346480-B1 COLOURING COMPOSITION KAO GERMANY GMBH (DE) 2016-01-06 — — EP disclosed
US-8795391-B2 Colouring composition KAO GERMANY GMBH (DE) 2014-08-05 — — US disclosed
US-8673022-B2 Colouring composition KAO GERMANY GMBH (DE) 2014-03-18 — — US disclosed
US-8668746-B2 Two-part hair colouring composition KAO GERMANY GMBH (DE) 2014-03-11 — — US disclosed
EP-2377511-A1 Colouring composition KPSS-Kao Professional Salon Services GmbH (DE) 2011-10-19 — — EP disclosed
EP-2377513-A1 Colouring composition KPSS-Kao Professional Salon Services GmbH (DE) 2011-10-19 — — EP disclosed
US-20110240052-A1 COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR KPSS-KAO PROFESSIONAL SALON SERVICES GMBH 2011-10-06 — — US disclosed
US-20110197912-A1 COLORING COMPOSITION KPSS-KAO PROFESSIONAL SAL SERVICES GMBH 2011-08-18 — — US disclosed
EP-2346481-A2 COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR KPSS-Kao Professional Salon Services GmbH (DE) 2011-07-27 — — EP disclosed
EP-2346480-A2 COLOURING COMPOSITION KPSS-Kao Professional Salon Services GmbH (DE) 2011-07-27 — — EP disclosed
WO-2010046077-A2 COLOURING COMPOSITION KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2010-04-29 — — WO disclosed
WO-2010046080-A2 COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2010-04-29 — — WO disclosed
EP-2177204-A1 Colouring composition KPSS-Kao Professional Salon Services GmbH (DE) 2010-04-21 — — EP disclosed
EP-2177205-A1 Composition for the permanent shaping of human hair KPSS-Kao Professional Salon Services GmbH (DE) 2010-04-21 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110197912-A1 COLORING COMPOSITION KRT18, POLL, POLQ KMT2A 758/4885MAPT 176/4885HAO1 2564/4885
US-20110240052-A1 COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR POLR1C, DRD3, DRD4 KMT2A 1457/4885MAPT 3299/4885HAO1 2767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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