Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ALPG | P10696 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.52 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7390863 | 1.00 | TP53 (0.64) | TP53SIRT2SMN1; SMN2GAALMNA | |
| SCHEMBL7397442 | 0.99 | TP53 (0.65) | TP53SIRT2SMN1; SMN2GAALMNA | |
| SCHEMBL7388416 | 0.92 | TP53 (0.65) | TP53SIRT2SMN1; SMN2GAALMNA | |
| SCHEMBL7389782 | 0.91 | KDM4E (0.61) | TP53SIRT2SMN1; SMN2GAALMNA | |
| SCHEMBL7394420 | 0.88 | SIRT2 (0.55) | TP53SIRT2SMN1; SMN2GAALMNA | |
| SCHEMBL7391936 | 0.86 | SMN1; SMN2 (0.49) | TP53SIRT2SMN1; SMN2GAALMNA | |
| SCHEMBL8267158 | 0.86 | SIRT2 (0.50) | TP53SIRT2SMN1; SMN2GAALMNA | |
| SCHEMBL7397513 | 0.84 | HDAC1 (0.51) | TP53SIRT2SMN1; SMN2GAALMNA | |
| SCHEMBL7394024 | 0.83 | KDM4E (0.65) | TP53SIRT2SMN1; SMN2GAALMNA | |
| SCHEMBL7397143 | 0.83 | SIRT2 (0.60) | TP53SIRT2SMN1; SMN2GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130333-A | VISION DEFECTS; CARDIOVASCULAR DISORDERS | MONSANTO COMPANY (US) | 2000-10-10 | — | — | US | disclosed |