Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.60 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7385375 | 0.87 | SIRT2 (0.52) | SIRT2SIRT1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7397442 | 0.84 | TP53 (0.65) | SIRT2SIRT1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7391995 | 0.83 | TP53 (0.64) | SIRT2SIRT1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7390863 | 0.83 | TP53 (0.64) | SIRT2SIRT1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7389782 | 0.82 | KDM4E (0.61) | SIRT2SIRT1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL22965154 | 0.82 | KDM4E (0.62) | ALDH1A1KDM4EHPGDHTTTP53 | |
| SCHEMBL7395324 | 0.82 | TSHR (0.62) | SIRT2SIRT1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7394024 | 0.82 | KDM4E (0.65) | SIRT2SIRT1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7394420 | 0.81 | SIRT2 (0.55) | SIRT2SIRT1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7387135 | 0.80 | SIRT2 (0.52) | SIRT2SIRT1ALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130333-A | VISION DEFECTS; CARDIOVASCULAR DISORDERS | MONSANTO COMPANY (US) | 2000-10-10 | — | — | US | disclosed |