Butyric Acid

Butyric Acid

SCHEMBL739375

CC(C)C(=O)O.CCCC(=O)O

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.72
HDAC3 O15379 1/20 0.72
HDAC1 Q13547 1/20 0.72
HDAC2 Q92769 1/20 0.72
HDAC8 Q9BY41 1/20 0.72
CYP1A2 P05177 1/20 0.50
AKR1B1 P15121 1/20 0.48
GPR84 Q9NQS5 7/20 0.46
PPARG P37231 7/20 0.46
PPARD Q03181 7/20 0.46
PPARA Q07869 7/20 0.46
HDAC11 Q96DB2 5/20 0.46
TSHR P16473 4/20 0.46
PTPN1 P18031 3/20 0.46
ALDH1A1 P00352 2/20 0.46
TLR2 O60603 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
FABP4 P15090 2/20 0.46
SLC22A6 Q4U2R8 1/20 0.46
SLC22A8 Q8TCC7 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyric Acid SCHEMBL28561915 1.00 FFAR3 (0.72) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL27846565 0.95 FFAR3 (0.65) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL5514388 0.95 FFAR3 (0.65) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL7818366 0.95 FFAR3 (0.65) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL10754251 0.93 FFAR3 (0.62) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL27473502 0.91 FFAR3 (0.59) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL19800894 0.89 FFAR3 (0.56) FFAR3HDAC3HDAC1HDAC2HDAC8
Lactic Acid SCHEMBL183593 0.86 FFAR3 (0.68) FFAR3HDAC3HDAC1HDAC2HDAC8
Methylmalonic Acid SCHEMBL2100642 0.86 FFAR3 (0.68) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL4578587 0.86 FFAR3 (0.77) FFAR3HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2844691-B1 PLASTICISER COMPOSITIONS COMPRISING GELIFICATION ACCELERATORS BASED ON ESTER(S) OF 1,4 : 3,6-DIANHYDROHEXITOL HAVING LOW MOLAR WEIGHT ROQUETTE FRERES (FR) 2019-08-14 EP claimed
EP-2844691-A2 PLASTICISER COMPOSITIONS COMPRISING GELIFICATION ACCELERATORS BASED ON ESTER(S) OF 1,4 : 3,6-DIANHYDROHEXITOL HAVING LOW MOLAR WEIGHT Roquette Frères (FR) 2015-03-11 EP claimed
WO-2013164545-A2 PLASTICISER COMPOSITIONS COMPRISING GELIFICATION ACCELERATORS BASED ON ESTER(S) OF 1,4 : 3,6-DIANHYDROHEXITOL HAVING LOW MOLAR WEIGHT ROQUETTE FRERES (FR) 2013-11-07 WO claimed
EP-0321272-B1 PROCESS FOR EXCHANGING DISPERSING MEDIUM OF TEREPHTHALIC ACID SLURRY MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-05-20 EP claimed
US-5008450-A Multi-stage separation from aliphatic carboxylic acid MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-04-16 US claimed
EP-0321272-A1 Process for exchanging dispersing medium of terephthalic acid slurry MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-06-21 EP claimed
US-11929171-B2 Methods for evaluation and treatment of glycemic dysregulation and atherosclerotic cardiovascular disease and applications thereof THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-03-12 US disclosed
US-20230190709-A1 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING VAGUS NERVE ASSOCIATED DISEASES, DISORDERS, AND CONDITIONS MarvelBiome, Inc. (US) 2023-06-22 US disclosed
CN-113467187-B Resin composition, resin film, and display device 吉林奥来德光电材料股份有限公司 2022-05-10 CN disclosed
CN-113467187-A Resin composition, resin film and display device 吉林奥来德光电材料股份有限公司 2021-10-01 CN disclosed
CN-107108452-B Hemiacetal pro-flavors 弗门尼舍有限公司 2020-10-13 CN disclosed
US-20200227166-A1 Methods for Evaluation and Treatment of Glycemic Dysregulation and Atherosclerotic Cardiovascular Disease and Applications Thereof THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2020-07-16 US disclosed
CN-105793749-B Polarizing film, polarizing film with adhesive layer, and image display device 日东电工株式会社 2020-04-24 CN disclosed
EP-0328954-A1 5-Cyano-2,4-diamino-thiazole derivatives BAYER AG (DE) 1989-08-23 EP disclosed
US-4612390-A PHOSPHINE PALLADIUM CATALYST ATLANTIC RICHFIELD COMPANY (US) 1986-09-16 US disclosed
EP-0043936-B1 METHOD FOR THE PREPARATION OF BENZO-1,2-DITHIOL-3-THIONES BASF Aktiengesellschaft (DE) 1984-09-05 EP disclosed
EP-0031430-B1 A METHOD FOR THE PRODUCTION OF ANTIBIOTIC C-15003 P-3 Takeda Chemical Industries, Ltd. (JP) 1983-12-28 EP disclosed
EP-0043936-A1 Method for the preparation of benzo-1,2-dithiol-3-thiones BASF Aktiengesellschaft (DE) 1982-01-20 EP disclosed
EP-0014402-A1 Novel 20-0-acylmaytansinoids, process for their preparation and pharmaceutical compositions containing them Takeda Chemical Industries, Ltd. (JP) 1980-08-20 EP disclosed
US-4124707-A 7α-Halogeno-3,20-dioxo-1,4-pregnadienes, methods for their manufacture, their use as anti-inflammatory agents, and pharmaceutical formulations useful therefor SCHERING CORPORATION (US) 1978-11-07 US disclosed