Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 4/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | PRKCG | P05129 | 2/20 | 0.33 |
| ▸ | PRKCB | P05771 | 2/20 | 0.33 |
| ▸ | PRKCH | P24723 | 2/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394225 | 1.00 | GRM2 (0.38) | GRM2PRKCAPRKCDTSHRHSD17B10 | |
| SCHEMBL7401295 | 0.83 | F2 (0.38) | PRKCAPRKCDBRD4 | |
| SCHEMBL7401296 | 0.83 | F2 (0.38) | PRKCAPRKCDBRD4 | |
| SCHEMBL7401650 | 0.81 | GRM2 (0.42) | GRM2PRKCAPRKCDTSHRHSD17B10 | |
| SCHEMBL7401646 | 0.81 | GRM2 (0.42) | GRM2PRKCAPRKCDTSHRHSD17B10 | |
| SCHEMBL7405665 | 0.81 | GRM2 (0.42) | GRM2PRKCAPRKCDTSHRHSD17B10 | |
| SCHEMBL7405668 | 0.81 | GRM2 (0.42) | GRM2PRKCAPRKCDTSHRHSD17B10 | |
| SCHEMBL7401654 | 0.81 | GRM2 (0.42) | GRM2PRKCAPRKCDTSHRHSD17B10 | |
| SCHEMBL7397474 | 0.81 | GRM2 (0.42) | GRM2PRKCAPRKCDTSHRHSD17B10 | |
| SCHEMBL7397468 | 0.81 | GRM2 (0.42) | GRM2PRKCAPRKCDTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646183-A | Phenyl amidine alkanoic acids useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1997-07-08 | — | — | US | disclosed |
| US-5612355-A | Phenyl amidine lactones useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1997-03-18 | — | — | US | disclosed |
| WO-1994000424-A1 | PHENYL AMIDINE ALKANOIC ACIDS AND LACTONES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-01-06 | — | — | WO | disclosed |