SCHEMBL739439

SCHEMBL739439

O=S(=O)(O)CCCCN(CCO)CCO

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.41
LMNA P02545 2/20 0.33
BLM P54132 2/20 0.33
PTGS1 P23219 1/20 0.33
PDE4A P27815 1/20 0.33
SLC6A6 P31641 1/20 0.33
CYP2C19 P33261 1/20 0.33
MAPT P10636 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
EGFR P00533 1/20 0.31
POLB P06746 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31
RAD52 P43351 1/20 0.31
RECQL P46063 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11236423 0.98 APP (0.39) APPLMNABLMPTGS1PDE4A
Trolamine SCHEMBL27898385 0.93 APP (0.42) APPLMNABLMPTGS1PDE4A
SCHEMBL8108004 0.93 APP (0.42) APPLMNABLMPTGS1PDE4A
SCHEMBL3684287 0.91 APP (0.41) APPLMNABLMPTGS1PDE4A
SCHEMBL28646235 0.89 APP (0.39) APPLMNABLMPTGS1PDE4A
SCHEMBL11237951 0.89 APP (0.39) APPLMNABLMPTGS1PDE4A
Trolamine SCHEMBL27850755 0.88 APP (0.42) APPLMNABLMPTGS1PDE4A
Potassium SCHEMBL31013623 0.87 APP (0.38) APPLMNABLMPTGS1PDE4A
SCHEMBL11238895 0.86 APP (0.41) APPLMNABLMPTGS1PDE4A
SCHEMBL22056603 0.84 APP (0.34) APPLMNABLMPTGS1PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230279290-A1 COMPOSITIONS AND METHODS FOR ASSAY MEASUREMENTS MESO SCALE TECHNOLOGIES LLC (US) 2023-09-07 US claimed
WO-2023129884-A1 METHODS FOR ELECTROCHEMILUMINESCENCE DETECTION MESO SCALE TECHNOLOGIES, LLC. (US) 2023-07-06 WO claimed
US-20210109100-A1 KITS SUITABLE FOR USE IN ELECTROCHEMILUMINESCENCE METHODS AND METHODS OF EFFECTING A SPECIFIC-BINDING NON-WASH ASSAY MESO SCALE TECHNOLOGIES, LLC. (US) 2021-04-15 US claimed
US-10753934-B2 Kits suitable for use in electrochemiluminescence methods and methods of effecting a specific-binding non-wash assay MESO SCALE TECHNOLOGIES, LLC. (US) 2020-08-25 US claimed
EP-1436598-B1 ASSAY BUFFER, COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME MESO SCALE TECHNOLOGIES LLC (US) 2013-11-27 EP claimed
EP-1893990-A2 ELECTROCHEMISTRY AND ELECTROGENERATED CHEMILUMINESCENCE WITH A SINGLE FARADAIC ELECTRODE THE UNIVERSITY OF TEXAS SYSTEM (US) 2008-03-05 EP claimed
EP-1436598-A4 ASSAY BUFFER, COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME MESO SCALE TECHNOLOGIES LLC (US) 2007-10-31 EP claimed
WO-2007053191-A9 ELECTROCHEMISTRY AND ELECTROGENERATED CHEMILUMINESCENCE WITH A SINGLE FARADAIC ELECTRODE UNIV TEXAS (US) 2007-08-09 WO claimed
WO-2007053191-A2 ELECTROCHEMISTRY AND ELECTROGENERATED CHEMILUMINESCENCE WITH A SINGLE FARADAIC ELECTRODE UNIVERSITY OF TEXAS SYSTEM (US) 2007-05-10 WO claimed
US-6919173-B2 Electrochemiluminescence; kinases; phosphatases MESO SCALE TECHNOLOGIES, LLC. (US) 2005-07-19 US claimed
EP-1436598-A1 ASSAY BUFFER, COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME Meso Scale Technologies LLC (US) 2004-07-14 EP claimed
US-20030175803-A1 Electrochemiluminescence; kinases; phosphatases MESO SCALE TECHNOLOGIES, LLC. 2003-09-18 US claimed
WO-2003023380-A1 ASSAY BUFFER, COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME MESO SCALE TECHNOLOGIES, LLC (US) 2003-03-20 WO claimed
US-20230279290-A1 COMPOSITIONS AND METHODS FOR ASSAY MEASUREMENTS MESO SCALE TECHNOLOGIES LLC (US) 2023-09-07 US disclosed
WO-2023129884-A1 METHODS FOR ELECTROCHEMILUMINESCENCE DETECTION MESO SCALE TECHNOLOGIES, LLC. (US) 2023-07-06 WO disclosed
US-20210109100-A1 KITS SUITABLE FOR USE IN ELECTROCHEMILUMINESCENCE METHODS AND METHODS OF EFFECTING A SPECIFIC-BINDING NON-WASH ASSAY MESO SCALE TECHNOLOGIES, LLC. (US) 2021-04-15 US disclosed
US-20050136048-A1 Electrochemiluminescence assays; aqueous reagent composition consisting of water, tripropylamine 50 mM-1000 mM and an electrolyte comprising a pH buffer selected from tris(hydroxymethyl)aminomethane and glycylglycine, pH of 6.5-8.5; improved sensitivity MESO SCALE TECHNOLOGIES, LLC. 2005-06-23 US disclosed
EP-1436598-A1 ASSAY BUFFER, COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME Meso Scale Technologies LLC (US) 2004-07-14 EP disclosed
US-20030175803-A1 Electrochemiluminescence; kinases; phosphatases MESO SCALE TECHNOLOGIES, LLC. 2003-09-18 US disclosed
WO-2003023380-A1 ASSAY BUFFER, COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME MESO SCALE TECHNOLOGIES, LLC (US) 2003-03-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050136048-A1 Electrochemiluminescence assays; aqueous reagent composition consisting of water, tripropylamine 50 mM-1000 mM and an electrolyte comprising a pH buffer selected from tris(hydroxymethyl)aminomethane and glycylglycine, pH of 6.5-8.5; improved sensitivity GNMT, TET1, MPG APP 1527/4885LMNA 1357/4885BLM 1122/4885
US-20030175803-A1 Electrochemiluminescence; kinases; phosphatases PRKACA, DUSP3, PPP6C APP 3936/4885LMNA 2517/4885BLM 1758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.