Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394683 | 1.00 | EPHX1 (0.32) | EPHX1HPGDCHRM2CHRM1CHRM3 | |
| SCHEMBL7394681 | 1.00 | EPHX1 (0.32) | EPHX1HPGDCHRM2CHRM1CHRM3 | |
| SCHEMBL10528950 | 0.86 | SPHK1 (0.35) | EPHX1HPGDSPHK1RECQL | |
| SCHEMBL7483186 | 0.85 | SPHK1 (0.32) | SPHK1 | |
| SCHEMBL7292716 | 0.85 | SPHK1 (0.32) | SPHK1 | |
| SCHEMBL7483173 | 0.85 | SPHK1 (0.32) | SPHK1 | |
| SCHEMBL7293176 | 0.83 | ACHE (0.32) | CHRM2CHRM1 | |
| SCHEMBL7293170 | 0.83 | ACHE (0.32) | CHRM2CHRM1 | |
| SCHEMBL7293173 | 0.83 | ACHE (0.32) | CHRM2CHRM1 | |
| SCHEMBL9556791 | 0.82 | SPHK1 (0.34) | EPHX1HPGDSPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |