⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL207518 | 0.72 | — | — | |
| SCHEMBL208475 | 0.69 | — | — | |
| SCHEMBL1270192 | 0.67 | — | — | |
| SCHEMBL737287 | 0.67 | — | — | |
| SCHEMBL308800 | 0.67 | — | — | |
| SCHEMBL10771642 | 0.67 | — | — | |
| SCHEMBL9303276 | 0.67 | — | — | |
| SCHEMBL5473399 | 0.67 | — | — | |
| SCHEMBL10653343 | 0.65 | — | — | |
| SCHEMBL5651965 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 432 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9145425-B2 | Cephem compound having catechol group | SHIONOGI & CO., LTD. (JP) | 2015-09-29 | — | — | US | claimed |
| JP-4650419-B2 | — | — | 2011-03-16 | — | — | JP | claimed |
| CN-100491358-C | Pyrimidinone compounds, compositions and methods | CYTOKINETICS INC SMITHKLINE BE (US) | 2009-05-27 | — | — | CN | claimed |
| US-7524594-B2 | Photosensitive dielectric resin compositions, films formed therefrom and semiconductor and display devices encompassing such films | PROMERUS LLC (US) | 2009-04-28 | — | — | US | claimed |
| EP-1778759-B1 | PHOTOSENSITIVE DIELECTRIC RESIN COMPOSITIONS AND THEIR USES | PROMERUS LLC (US) | 2008-11-12 | — | — | EP | claimed |
| US-7407961-B2 | Pyrazine derivatives and pharmaceutical use thereof | ASTELLAS PHARMA INC. (JP) | 2008-08-05 | — | — | US | claimed |
| EP-1778759-A1 | PHOTOSENSITIVE DIELECTRIC RESIN COMPOSITIONS AND THEIR USES | Promerus, LLC (US) | 2007-05-02 | — | — | EP | claimed |
| JP-2007510620-A | — | — | 2007-04-26 | — | — | JP | claimed |
| EP-1682534-A2 | PYRIMIDIN-4-ONE COMPOUNDS, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2006-07-26 | — | — | EP | claimed |
| EP-1678160-A1 | PYRAZINE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | Astellas Pharma Inc. (JP) | 2006-07-12 | — | — | EP | claimed |
| US-20050197327-A1 | Compounds, compositions, and methods | CYTOKINETICS, INCORPORATED | 2005-09-08 | — | — | US | claimed |
| CN-1665788-A | Pyrimidinone compounds, compositions and methods | CYTOKINETICS INC (US) | 2005-09-07 | — | — | CN | claimed |
| US-20050113387-A1 | Pyrazine derivatives and pharmaceutical use thereof | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-05-26 | — | — | US | claimed |
| WO-2005041888-A2 | PYRIMIDIN-4-ONE COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-05-12 | — | — | WO | claimed |
| WO-2005040151-A1 | PYRAZINE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | ASTELLAS PHARMA INC. (JP) | 2005-05-06 | — | — | WO | claimed |
| EP-0472925-B1 | Substituted pyridins | BAYER AG (DE) | 1994-08-31 | — | — | EP | claimed |
| US-4801703-A | PHOSPHORUS COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-01-31 | — | — | US | claimed |
| EP-0102740-B1 | N-FORMYL AND N-HYDROXYMETHYL-3-PHENOXY-1-AZETIDINECARBOXAMIDES AND THEIR PREPARATION AND USE | A.H. ROBINS COMPANY, INCORPORATED (US) | 1986-11-05 | — | — | EP | claimed |
| EP-0078266-B1 | CROSS-LINKABLE POLYMER COMPOSITION SOLUBLE IN AN AQUEOUS MEDIUM, PREPARATION AND UTILIZATION THEREOF | CASSELLA Aktiengesellschaft (DE) | 1985-11-13 | — | — | EP | claimed |
| EP-0030030-A1 | Derivatives of 2-aminoethanol, processes for their preparation, pharmaceutical compositions containing such compounds and the use the latter | CIBA-GEIGY AG (CH) | 1981-06-10 | — | — | EP | claimed |