Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 2/20 | 0.74 |
| ▸ | PLAU | P00749 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | WDR5 | P61964 | 3/20 | 0.56 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6435605 | 0.85 | PLG (0.72) | PLGPLAUMEN1KMT2APOLB | |
| SCHEMBL6436568 | 0.85 | PLG (0.56) | PLGPLAUMEN1KMT2APOLB | |
| Trifluoroacetic Acid SCHEMBL6436933 | 0.80 | PLG (0.65) | PLGPLAUMEN1KMT2APOLB | |
| SCHEMBL6432817 | 0.79 | PLG (0.74) | PLGPLAUMEN1KMT2APOLB | |
| SCHEMBL17331335 | 0.77 | POLB (0.78) | MEN1KMT2APOLBWDR5PFKFB3 | |
| SCHEMBL11887776 | 0.76 | MEN1 (0.75) | PLGPLAUMEN1KMT2APOLB | |
| SCHEMBL24215474 | 0.76 | MEN1 (0.70) | PLGPLAUMEN1KMT2APOLB | |
| SCHEMBL30515749 | 0.76 | MEN1 (0.70) | PLGPLAUMEN1KMT2APOLB | |
| SCHEMBL29875309 | 0.76 | PFKFB3 (0.71) | MEN1KMT2APOLBPFKFB3MAPT | |
| SCHEMBL29369447 | 0.76 | PFKFB3 (0.71) | MEN1KMT2APOLBPFKFB3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242120-A2 | COMBINATIONS OF GROWTH FACTORS AND I:UPA OR I:MMP FOR THE TREATMENT OF DAMAGED TISSUE | Pfizer Limited (GB) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001049309-A2 | COMBINATIONS OF GROWTH FACTORS AND I: UPA OR I: MMP FOR THE TREATMENT OF DAMAGED TISSUE | PFIZER LIMITED (GB) | 2001-07-12 | — | — | WO | disclosed |