Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | SLC25A1 | P53007 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.60 |
| ▸ | WDR5 | P61964 | 2/20 | 0.59 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | PLG | P00747 | 1/20 | 0.55 |
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.54 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30515749 | 1.00 | MEN1 (0.70) | MEN1KMT2ASLC25A1POLBCASP3 | |
| SCHEMBL7371667 | 0.92 | KMT2A (0.62) | MEN1KMT2ASLC25A1POLBCASP3 | |
| SCHEMBL6205157 | 0.86 | KMT2A (0.53) | MEN1KMT2ASLC25A1POLBCASP3 | |
| SCHEMBL6204952 | 0.86 | KMT2A (0.53) | MEN1KMT2ASLC25A1POLBCASP3 | |
| SCHEMBL6205161 | 0.86 | KMT2A (0.53) | MEN1KMT2ASLC25A1POLBCASP3 | |
| SCHEMBL3619380 | 0.85 | SLC25A1 (0.67) | MEN1KMT2ASLC25A1MAPTDNMT1 | |
| SCHEMBL3615295 | 0.84 | VCAM1 (0.59) | MEN1KMT2ASLC25A1MAPTDNMT1 | |
| SCHEMBL5059972 | 0.83 | KMT2A (0.57) | MEN1KMT2ASLC25A1POLBWDR5 | |
| SCHEMBL8366106 | 0.81 | CASP3 (0.81) | MEN1KMT2ASLC25A1POLBCASP3 | |
| SCHEMBL11752812 | 0.81 | VCAM1 (0.60) | MEN1KMT2ASLC25A1MAPTDNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022013295-A1 | THE ROLE OF PMCIC IN THE TUMOR MICROENVIRONMENT | UNIVERSITÄTSKLINIKUM REGENSBURG (DE) | 2022-01-20 | — | — | WO | disclosed |